Protein Alignment Ugt35E2 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 557
• Identity: 149/557 - (26%)
• Similarity: 256/557 - (45%)
• Gaps: 74/557 - (13%)

  Fly     7 VLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPVANI 71
            |.|:..|:......|:|..::|.: |:.. ||:......::.|...|:::..::|.      :||
 Frog    11 VYRVFALLFLGRVQLIEAEKLLAI-PLDG-SHWLSMRILVESLGQRGNQVVVLAPH------SNI 67

  Fly    72 H----------DIPVPELFDNIEEIVGNLTNRKGT--------WNEFEYINQYTLGLVEKVLEND 118
            |          ..|||...:.::|.:....|...|        .|.::.|...| |:|....::.
 Frog    68 HIHPSENYILRTYPVPYSKELLKEQMVKSANDVFTKRPLLDKITNMYQRITNVT-GIVFSACQHL 131

  Fly   119 GVRREILQP-ESLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKIDELVGNV-SPLAYL 181
            ...:||:|. :...||..::|.:....:. :|.|...|.:.:. ||....||.|.... |||:|:
 Frog   132 LHSKEIMQELQESAFDAALIDPFFPCGMI-VAEYLHLPSVYLL-YGLPCGIDRLATQCPSPLSYV 194

  Fly   182 --------QSPSFN--------WFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKI 230
                    ...||.        | .:||:   |.:.:....|.:...:.|.|
 Frog   195 PRHFTGNTDHMSFPQRLKNALLW-PVDTF---LCNLLYSPYAQLASEFLHRE------------- 242

  Fly   231 ADKRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMH-VDQQPKALPQDLEDFIQGAGEHG 294
               .::.::....::.|:...|....|||.:||::.|||:: |.:|  .|.|:.|..:..:||||
 Frog   243 ---MTILQLYSQTSVWLMKTDFVFDYPRPLMPNMVFVGGINCVGEQ--HLNQEFEKLVNSSGEHG 302

  Fly   295 VIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHP 359
            .:.||||:.|  ..:..::...:.:...|:||::.|::......::..|..:..|.||.|:||||
 Frog   303 FVVFSLGSMV--SEIPMNKAMDIAEALKSIPQKVFWRYTGKAPPNLGENTHLVKWLPQNDLLAHP 365

  Fly   360 NVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQ 424
            ..:.||||.|.....|.|...|||:.:|.|.||..|.:.|:::|.||.||...||.::..:.:..
 Frog   366 KARAFITHAGSHGIYEGICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVRA 430

  Fly   425 LLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGT 489
            ::....:....:|.:..:.|:|::|||.|:.|..:|:|||||||:|.|..:|::..|:||||:|.
 Frog   431 VINNPVYKENIQRMSSLHLDRPIHPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYYSLDVIGF 495

  Fly   490 FLLAVWAILSIVVLCAIKLLRAILK--SKKGNISPKQ 524
            .|..:...|.|.:.|...:.|...|  |||...|..|
 Frog   496 LLAVLLTALFISLKCCTFVFRRCFKRNSKKQRKSKSQ 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	108/448 (24%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	92/272 (34%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	140/529 (26%)