Protein Alignment Ugt35E2 and ugt2b5

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001170816.3
• Gene: ugt2b5 / 100384902
• ZFINID: ZDB-GENE-100402-3
• Length: 527
• Species: Danio rerio
• Alignment Length: 555
• Identity: 145/555 - (26%)
• Similarity: 259/555 - (46%)
• Gaps: 78/555 - (14%)

  Fly     8 LRLIVLVVALLPVLLEG--ARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSP--------- 61
            :||:|..::||.|...|  ..||..:  ...||:.:....|..|...||.:|.:.|
Zfish     1 MRLVVCFLSLLTVFSAGQCGNILVWY--TEGSHWINLKIVLDTLLDRGHNVTVLVPDGALFMKAK 63

  Fly    62 ---------FPLKEPVANIHDIPVPELFDNIEEI-VGNLTNRKGTWNEFEYINQYTLGLVEKVLE 116
                     |.:.:...::.|     .||.:... |..:.|......:.::.|   ||...:.:.
Zfish    64 ESDRFSYQHFSVSKSAQDMQD-----FFDELMRFSVFEMDNSSFLEIQMKFFN---LGSQHQDMS 120

  Fly   117 ---NDGVRREILQPESL------QFDLIIVDLWRLDALYG----LAAYFDAPIIGIASYGTDWKI 168
               .||:   :..||.:      :||:::     .|.:|.    :|...:.|::....:......
Zfish   121 LSYCDGI---LKSPELMDKLKKGKFDVVL-----SDPMYPCSDIMAEELNVPLVYTFRFSVAHAA 177

  Fly   169 DELVGNV-SPLAYLQSPSFNWFDLDTYGGR----LGHFVDQSMAWINWHWRHEERHEAVYRKYFP 228
            :.:.|.: :|.:|:........|..::..|    |.:....:::.:.|     .|.:..|.:||.
Zfish   178 ERMCGQIPAPPSYVPGAMSKLTDRMSFTERIFNMLFYLSQDTLSRLIW-----RRFDNYYTEYFG 237

  Fly   229 KIADKRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEH 293
            :   ..|..|:.....:.|:..::....|||:|||...:||:|. ...|.||:|:|:|:|.:|:.
Zfish   238 R---STSYCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHC-TPAKPLPKDMEEFVQSSGDD 298

  Fly   294 GVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAH 358
            |::.|:||:.:  ..:.|:....:....|.:||::||::..::...:..|..|..|.||.|:|.|
Zfish   299 GIVVFTLGSMI--DKVPKEMSNRIASALAQIPQKVLWRYGGEKPDTLGENTRIYKWMPQNDLLGH 361

  Fly   359 PNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVL-NYRDMTSDEFKDTI 422
            |..:.||||||.....|.|:.||||:|:|.|.||..||.|:..:|..:|: :.:.|...|..|.:
Zfish   362 PKTRAFITHGGTNGVYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKL 426

  Fly   423 HQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVL 487
            :.::.:.|:...|.|.:..:.|:||.|||.:::|..:|:|:|||.|:||...||.:..||.|||.
Zfish   427 NTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVF 491

  Fly   488 GTFLLAVWAILSIVVLCAIK-----LLRAILKSKK 517
             .||..|   |::|:....|     ::|...:||:
Zfish   492 -AFLTTV---LTLVLYICFKMAKFFIMRCCFRSKR 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	105/449 (23%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	95/275 (35%)
ugt2b5	NP_001170816.3	None