Protein Alignment Ugt35E2 and ugt2a1

DIOPT Version :10

• Sequence 1: NP_652623.2
• Gene: Ugt35E2 / 53506
• FlyBaseID: FBgn0040255
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001177979.1
• Gene: ugt2a1 / 100006320
• ZFINID: ZDB-GENE-080721-20
• Length: 539
• Species: Danio rerio
• Alignment Length: 550
• Identity: 160/550 - (29%)
• Similarity: 266/550 - (48%)
• Gaps: 56/550 - (10%)

  Fly    11 IVLVVALL----PVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSV----SPFPLKEP 67
            :.|::|||    .:.:.|.:|| |:| ...||:.:....|..|...||.||.|    :|.....|
Zfish     9 VFLLLALLLNQNLLCVSGGKIL-VWP-AEFSHWLNIKVILDVLIERGHNITVVTHTATPSVQTTP 71

  Fly    68 VA--NIHDIPVP----ELFDNIEEIV----GNLTNRKGTWNEFEYINQYTLGLVEKVLENDGV-- 120
            .|  |...:.||    |:.||:|.::    .:|.|........:.....|....:..:..:.:
Zfish    72 SAGYNAEILQVPYTKQEIVDNLERMLKYWTHDLPNDNIITASLKIHEMITTATAQNKITCNALFS 136

  Fly   121 RREILQPESLQ-FDLIIVDLWRLDALY--G--LAAYFDAPIIGIASYGTDWKIDELVGNV-SPLA 179
            |.::|:...:: ||:|:.     |.||  |  ||...|.|:|....:.....::.|.|.: :|.:
Zfish   137 RADLLEKWKMEKFDVILA-----DPLYICGEILAQKLDIPLIFSLRFTFGNTLERLCGQMPAPPS 196

  Fly   180 YLQSPSFNWFDLDTYGGRLGHFVDQSM------AWINWHWRHEERHEAVYRKYFPKIADK-RSLS 237
            |:.:.:....|...:..||.:|:...|      ....:.|.|          |:.::..| .::.
Zfish   197 YVPAVASEKTDQMDFIDRLKNFLFYGMQDFLFYLVTKFKWDH----------YYSEVLGKPTTMC 251

  Fly   238 EITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGT 302
            |......:.|:..::....|||:.||...|||:|. :..|.|.:::|:|:|.:|:|||:.||||:
Zfish   252 ETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHC-KPAKPLSKEMEEFVQSSGDHGVVVFSLGS 315

  Fly   303 NVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITH 367
            .:  :||:.:|...:......:||:::|::.......:..|..|..|.||.|:|.||..|.||||
Zfish   316 MI--KNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITH 378

  Fly   368 GGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFG 432
            ||.....|.|:.||||:|||.|.||..|:.|:|.:|..:||:...:.|.:..|.:..:|...|:.
Zfish   379 GGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYK 443

  Fly   433 VKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAI 497
            ....|.:..:.||||.|||.|::|..:|:|:|||.|:||....|.:..||.||| ..|||::.|:
Zfish   444 ESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDV-AAFLLSIAAL 507

  Fly   498 LSI--VVLCAIKLLRAILKSKKGNISPKQK 525
            ::.  |..|.....|.:.|::....:.|.|
Zfish   508 ITFLWVKACCFLFRRCVRKTRPERKTQKSK 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E2	NP_652623.2	MGT	31..443	CDD:273616	119/440 (27%)
		Glycosyltransferase_GTB-type	<247..517	CDD:471961	99/271 (37%)
ugt2a1	NP_001177979.1	UDPGT	27..526	CDD:278624	152/519 (29%)