DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35E1 and UGT74B1

DIOPT Version :9

Sequence 1:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_173820.1	Gene:	UGT74B1 / 839022	AraportID:	AT1G24100	Length:	460	Species:	Arabidopsis thaliana

Alignment Length:	513	Identity:	96/513 - (18%)
Similarity:	170/513 - (33%)	Gaps:	173/513 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LALFPVPSHSHYYHALPYLKNLASLGHEIT----------SVSPFPSEEPVKNIYDIYVPEVLNS 78
            :.:.|.|...|....:.:.|.|.|...::|          ..:|..|.||:.:.:| ::|..:..
plant    12 VVILPYPVQGHLNPMVQFAKRLVSKNVKVTIATTTYTASSITTPSLSVEPISDGFD-FIPIGIPG 75

  Fly    79 FDELLKQMTTPKNTWEFFDATNE-FVYNITKDVFNNDGVRREILRPGKAQFDLII---------V 133
            |.               .|..:| |..|                  |.....|:|         :
plant    76 FS---------------VDTYSESFKLN------------------GSETLTLLIEKFKSTDSPI 107

  Fly   134 DIWKYDAF------------YSLAAYFEAPIIGLAPCGIDWKIDEMVG--------NPSPMSYLQ 178
            |...||:|            .|.|::|..   .|..|.:..|...  |        |.:|.....
plant   108 DCLIYDSFLPWGLEVARSMELSAASFFTN---NLTVCSVLRKFSN--GDFPLPADPNSAPFRIRG 167

  Fly   179 SPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPK--------------IAET 229
            .||.....|.:|.||              ||....:|..:....||.              :.||
plant   168 LPSLSYDELPSFVGR--------------HWLTHPEHGRVLLNQFPNHENADWLFVNGFEGLEET 218

  Fly   230 KPLSEISQDIALVLVNQHFTLGP--PRPYVPNVIEVGGMHIDEQP------KALAQDLEDFIQGS 286
            :.......|.....:     :||  |..|:.:.:|      |::.      |.::::..::::..
plant   219 QDCENGESDAMKATL-----IGPMIPSAYLDDRME------DDKDYGASLLKPISKECMEWLETK 272

  Fly   287 GEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQR---------------VLWKFEDEELQDI 336
            ....|.:.|.|                  :||.|.::               .||..::..:..:
plant   273 QAQSVAFVSFG------------------SFGILFEKQLAEVAIALQESDLNFLWVIKEAHIAKL 319

  Fly   337 P--------SNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTN-- 391
            |        ...|:..|..|.::|||..:..|:||.|..||:|.:..|.||:|:|.:.||..:
plant   320 PEGFVESTKDRALLVSWCNQLEVLAHESIGCFLTHCGWNSTLEGLSLGVPMVGVPQWSDQMNDAK 384

  Fly   392 -VDHIKKHGFCLSLNYHD--MTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPL 446
             |:.:.|.|:.......:  :.|:|| ...|:.:.|....|..|.:..:::|..:|.:
plant   385 FVEEVWKVGYRAKEEAGEVIVKSEEL-VRCLKGVMEGESSVKIRESSKKWKDLAVKAM 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	96/513 (19%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	94/504 (19%)
UGT74B1	NP_173820.1	Glycosyltransferase_GTB-type	7..455	CDD:415824	96/513 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050