DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35E1 and UGT76B1

DIOPT Version :9

Sequence 1:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_187742.1	Gene:	UGT76B1 / 820307	AraportID:	AT3G11340	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	110/495 - (22%)
Similarity:	172/495 - (34%)	Gaps:	144/495 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ILALFPVPSHSHYYHALPYLKNLASL----GHEITSV-----SPFPSEEPVKNIYDI-------- 70
            ::.|||.|...|    |..:..||::    |..||.:     ||..|..|......|
plant     9 VIFLFPFPLQGH----LNPMFQLANIFFNRGFSITVIHTEFNSPNSSNFPHFTFVSIPDSLSEPE 69

  Fly    71 YVPEV------LNS-----FDELLKQMTT--PKNTWEFFDATNEFVYNITKDVFNNDGVRREILR 122
            ..|:|      |||     |.:.||::.:  |.......||...|.:::| :.||   ..|.:||
plant    70 SYPDVIEILHDLNSKCVAPFGDCLKKLISEEPTAACVIVDALWYFTHDLT-EKFN---FPRIVLR 130

  Fly   123 PGKAQFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNP------SPMSYLQSPS 181
                     .|::..:.||.......|...:.|.....|..:.|:   |      .|....:.|.
plant   131 ---------TVNLSAFVAFSKFHVLREKGYLSLQETKADSPVPEL---PYLRMKDLPWFQTEDPR 183

  Fly   182 S-------YLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDI 239
            |       .:.:|.:..|.:.:.:|                          ..||..|.|...:.
plant   184 SGDKLQIGVMKSLKSSSGIIFNAIE--------------------------DLETDQLDEARIEF 222

  Fly   240 ALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLE--DFIQGSGEHGVIYFSLGTNVRT 302
            .:.|    |.:||...||.          ......||.|:.  .::.....:.|||.|||:....
plant   223 PVPL----FCIGPFHRYVS----------ASSSSLLAHDMTCLSWLDKQATNSVIYASLGSIASI 273

  Fly   303 KNMVDDRKRILIEAFG--SLPQRVLWKFE------DEELQDIPSNVL--------VRKWLPQQDL 351
                 |....|..|:|  :..|..||...      .|.::.:|...:        :.||.||.::
plant   274 -----DESEFLEIAWGLRNSNQPFLWVVRPGLIHGKEWIEILPKGFIENLEGRGKIVKWAPQPEV 333

  Fly   352 LAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIK---KHGFCLSLNYHD----- 408
            |||.....|:||.|..||:|.|....||:..|.|.||..|..:|.   |.|..|......
plant   334 LAHRATGGFLTHCGWNSTLEGICEAIPMICRPSFGDQRVNARYINDVWKIGLHLENKVERLVIEN 398

  Fly   409 -----MTS---DELKATILQLLTEKRFEVTARIAGARYRD 440
                 |||   :|::..|:.:  ::..|...::.|:.:|:
plant   399 AVRTLMTSSEGEEIRKRIMPM--KETVEQCLKLGGSSFRN 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	110/495 (22%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	106/485 (22%)
UGT76B1	NP_187742.1	Glycosyltransferase_GTB-type	1..444	CDD:415824	110/495 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050