Protein Alignment Ugt35E1 and ugt2a4

DIOPT Version :10

• Sequence 1: NP_652622.3
• Gene: Ugt35E1 / 53504
• FlyBaseID: FBgn0040253
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001170804.2
• Gene: ugt2a4 / 791613
• ZFINID: ZDB-GENE-080721-23
• Length: 533
• Species: Danio rerio
• Alignment Length: 576
• Identity: 151/576 - (26%)
• Similarity: 265/576 - (46%)
• Gaps: 103/576 - (17%)

  Fly     2 LASGLFYLIILLFPGFLYG--ARILALFPVP-SHSHYYHALPYLKNLASLGHEIT----SVSP-F 58
            :.||.. |:.||..|...|  .|:|.:   | .:||:::....::.|....|.:|    |.|| .
Zfish     1 MTSGAL-LVCLLLCGVDVGWSGRVLVM---PGEYSHWHNMRAIIEALVDRNHSVTVLVSSSSPTV 61

  Fly    59 PSEEPVKNIYDIY--------VPEVLNSFDELLKQMTTPK-----NTWEFFDATNEFVYNITKDV 110
            |..:..:..|.::        ...:.:.|..|..:.|..|     ..|...........::.:.:
Zfish    62 PHTQKARFDYHVFKVNMDKEEAKVIWSDFTHLWMKETDSKLERGFLIWRVMSNFRRLAADVCRSL 126

  Fly   111 FNNDGVRREILRPGKAQFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCG---------------- 159
            ..||.:.:.:   |::.:|::                |..|::   ||.
Zfish   127 LQNDDLLQML---GESHYDVL----------------FSDPMM---PCSDLMAQTLNIPQVISLR 169

  Fly   160 --IDWKIDEMVGN-PSPMSYLQSP--SSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALY 219
              ..:..:.|.|. |:|.||:.:.  :.:|.:..:|..||.:::...|            |..::
Zfish   170 LTFAYTFERMCGQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYFI------------HTTVF 222

  Fly   220 K--------KYFPKIAETKP--LSEISQDIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKA 274
            :        :.:.:| ..||  :.|......:.|:..::....|||:.||...|||:|. :..|.
Zfish   223 RLNTMLTVDRLYTEI-RGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHC-KPAKP 285

  Fly   275 LAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQRVLWKFEDEELQDIPSN 339
            |::::|:|:|.||:|||:.||||:.:  ||:..:|...:..|.|.:||:|:|::..:..:.:..|
Zfish   286 LSKEMEEFVQSSGDHGVVVFSLGSMI--KNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPN 348

  Fly   340 VLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSL 404
            ..:..|:||.|||.|||.|.||||||.....|:|::|.||:|||.|.||..|:.|:|..|..:.|
Zfish   349 TKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVL 413

  Fly   405 NYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAG 469
            :.:.:.|.:|...:..:|....::.:.......:.|||||||:.||:|..:|:|:|||.|:||..
Zfish   414 DINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQA 478

  Fly   470 RKLSFFTHHSLDVLGTVLLVILLVIIAILLIIVFSVCKISKNISTRLVVKKQRKQK 525
            .:||::.:|.|||     ...||.|.|::..:....|    ....|..|:|.|.::
Zfish   479 HELSWYQYHCLDV-----AAFLLSIAALITFLWVKAC----CFLFRRCVRKTRPER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	Glycosyltransferase_GTB-type	33..484	CDD:471961	132/499 (26%)
ugt2a4	NP_001170804.2	UDPGT	21..520	CDD:278624	142/548 (26%)