Protein Alignment Ugt35E1 and Ugt2a2

DIOPT Version :10

• Sequence 1: NP_652622.3
• Gene: Ugt35E1 / 53504
• FlyBaseID: FBgn0040253
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 524
• Identity: 159/524 - (30%)
• Similarity: 256/524 - (48%)
• Gaps: 81/524 - (15%)

  Fly    33 SHYYHALPYLKNLASLGHEITSVSPFPSE--------EPVKNIYDIYVPEVLNSFDELLKQM--- 86
            ||:.:....|:.|....|.:|.::  |||        :...|..:|.|....:..||:::.|
Mouse    32 SHWLNIKILLEELVQRNHSVTVLA--PSETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIAL 94

  Fly    87 -----TTPKNTWEFFDATNEFV---YNITKD----VFNNDGVRREILRPGKAQFDLIIVD----- 134
                 .||...|.|:......:   |...|.    |.||..|...:.:.|   ||:::.|
Mouse    95 WLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERLQKGG---FDVLLADPVTMC 156

  Fly   135 ----------IWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDT 189
                      .:.|...:|.|...|      ..||   ||      |:|:||:.:..|.|.:..:
Mouse   157 GELVALKLGIPFVYTLRFSPAFTVE------RHCG---KI------PAPISYVPAALSELTDQMS 206

  Fly   190 FGGRVAHVVEVAIS-------WFNWHWRYEQKHEALYKKYFPKI-AETKPLSEISQDIALVLVNQ 246
            ||.||.:::..::.       |..|:            .|:.|: .....|.|......:.|:..
Mouse   207 FGERVKNIISYSLQDYIFKTYWGEWN------------SYYSKVLGRPTTLCETMGKAEIWLMRT 259

  Fly   247 HFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKR 311
            ::....||||:||...|||:|. :..|.|.:::|:|:|.|||||::.||||:.|  ||:.|::..
Mouse   260 YWDFEFPRPYLPNFEFVGGLHC-KPAKPLPKEMEEFVQTSGEHGIVVFSLGSMV--KNLTDEKAN 321

  Fly   312 ILIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYG 376
            ::..|...:||:|||:::.:....:.||..:..|:||.|||.|||.:.||||||.....|:|::|
Mouse   322 LIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHG 386

  Fly   377 KPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQ 441
            .||:|:|.|.||..|:.|:|..|..:.:|.:.|||.:|...:..::.|..::..|......:.||
Mouse   387 IPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQ 451

  Fly   442 PMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIVFSVC 506
            |:|||:.||:|..:|:|||||.|:|||...||:|.:|||||:|.:|..:...|:.:....:|...
Mouse   452 PVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQ 516

  Fly   507 KISK 510
            |:.|
Mouse   517 KVGK 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	Glycosyltransferase_GTB-type	33..484	CDD:471961	153/496 (31%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	157/518 (30%)