Protein Alignment Ugt35E1 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_652622.3
• Gene: Ugt35E1 / 53504
• FlyBaseID: FBgn0040253
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 524
• Identity: 159/524 - (30%)
• Similarity: 256/524 - (48%)
• Gaps: 81/524 - (15%)

  Fly    33 SHYYHALPYLKNLASLGHEITSVSPFPSE--------EPVKNIYDIYVPEVLNSFDELLKQM--- 86
            ||:.:....|:.|....|.:|.::  |||        :...|..:|.|....:..||:::.|
Mouse    32 SHWLNIKILLEELVQRNHSVTVLA--PSETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIAL 94

  Fly    87 -----TTPKNTWEFFDATNEFV---YNITKD----VFNNDGVRREILRPGKAQFDLIIVD----- 134
                 .||...|.|:......:   |...|.    |.||..|...:.:.|   ||:::.|
Mouse    95 WLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERLQKGG---FDVLLADPVTMC 156

  Fly   135 ----------IWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDT 189
                      .:.|...:|.|...|      ..||   ||      |:|:||:.:..|.|.:..:
Mouse   157 GELVALKLGIPFVYTLRFSPAFTVE------RHCG---KI------PAPISYVPAALSELTDQMS 206

  Fly   190 FGGRVAHVVEVAIS-------WFNWHWRYEQKHEALYKKYFPKI-AETKPLSEISQDIALVLVNQ 246
            ||.||.:::..::.       |..|:            .|:.|: .....|.|......:.|:..
Mouse   207 FGERVKNIISYSLQDYIFKTYWGEWN------------SYYSKVLGRPTTLCETMGKAEIWLMRT 259

  Fly   247 HFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKR 311
            ::....||||:||...|||:|. :..|.|.:::|:|:|.|||||::.||||:.|  ||:.|::..
Mouse   260 YWDFEFPRPYLPNFEFVGGLHC-KPAKPLPKEMEEFVQTSGEHGIVVFSLGSMV--KNLTDEKAN 321

  Fly   312 ILIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYG 376
            ::..|...:||:|||:::.:....:.||..:..|:||.|||.|||.:.||||||.....|:|::|
Mouse   322 LIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHG 386

  Fly   377 KPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQ 441
            .||:|:|.|.||..|:.|:|..|..:.:|.:.|||.:|...:..::.|..::..|......:.||
Mouse   387 IPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQ 451

  Fly   442 PMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIVFSVC 506
            |:|||:.||:|..:|:|||||.|:|||...||:|.:|||||:|.:|..:...|:.:....:|...
Mouse   452 PVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQ 516

  Fly   507 KISK 510
            |:.|
Mouse   517 KVGK 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	138/473 (29%)
		UDPGT	33..484	CDD:278624	153/496 (31%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	157/518 (30%)
		egt	<267..487	CDD:223071	93/222 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840197
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790