DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35E1 and Ugt317A1

DIOPT Version :9

Sequence 1:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	535	Identity:	138/535 - (25%)
Similarity:	239/535 - (44%)	Gaps:	86/535 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IILLFPGFLYG-----ARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYD 69
            |:|...|...|     |:||.|||..:..|:......:..||:..|.|...:.....|.:.|:.:
  Fly     9 ILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVTE 73

  Fly    70 IYVPEVLNSFDELLKQMTTPKNTWEF----FDATNEFVYNI---TKDVFNNDGVRREILRPG--K 125
            ....| ...:.||.||.....|..:.    .:...:.:.::   ..|.|......:::|:..  :
  Fly    74 TVTAE-FPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEPIQKLLKMSYLE 137

  Fly   126 AQFDLIIVDIWKYDAFYSLAAYFEAPIIGL------------------APCG-IDWKIDEMVGNP 171
            ..||:|:||.:..:|..:|.|..:.|::|:                  |.|. ||::.|:
  Fly   138 FDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPAACSPIDFERDQ----- 197

  Fly   172 SPMSYLQSPSSYLYNL------------DTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFP 224
            ..||:    |..|.|:            |.:||:                      |.|..|||
  Fly   198 PEMSF----SVRLGNIRTCIARRKQFIKDHYGGQ----------------------EQLVTKYF- 235

  Fly   225 KIAETKPLSEISQDIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEH 289
            ::..:.|..:.|| ::::|:|.|..|..|:..:..:|..||:|| ..||.|..:::.|:: ....
  Fly   236 QLQSSIPELQASQ-LSVLLLNSHVPLITPKVSIQQIIPAGGLHI-RGPKELPWNVKRFLE-EARP 297

  Fly   290 GVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQRVLWKFED-EELQDIPSNVLVRKWLPQQDLLA 353
            |.||..||.......:..::...|...|.:..|.::|...| :.|:.:|.||:::..:||.|:||
  Fly   298 GAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILA 362

  Fly   354 HPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATI 418
            ||:||.|:|:|.:.:..|.|....|:||||.|..:..|::...:.|..|.|...::|::.|...:
  Fly   363 HPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAV 427

  Fly   419 LQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVL 483
            .:||.|..|::|.|.....:||:|:..|.:|::|.:||.||||...:|..|..:|....|..|:.
  Fly   428 DRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLF 492

  Fly   484 ----GTVLLVILLVI 494
                |...||:.|::
  Fly   493 VFYAGIATLVVSLLV 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	127/496 (26%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	124/495 (25%)
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	126/490 (26%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	134/519 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970