Protein Alignment Ugt35E1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_652622.3
• Gene: Ugt35E1 / 53504
• FlyBaseID: FBgn0040253
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_787040.2
• Gene: Ugt1a8 / 301595
• RGDID: 708474
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 169/558 - (30%)
• Similarity: 270/558 - (48%)
• Gaps: 82/558 - (14%)

  Fly     9 LIILLF--PGFLYGARILALFPVP-SHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNI--- 67
            |.:.||  .||....|:|.   || ..||::.....::.|:..|||:..|.|..|....|::
  Rat    12 LCVCLFLASGFAQAGRLLV---VPMDGSHWFTMQMIVEKLSHRGHEVVVVIPEVSWHMGKSLNFT 73

  Fly    68 ---YDI-YVPEVLNSFDELLKQMTTPKNTWE----------------FFDATNEFVYNITKDVFN 112
               |.: |..|.||...:....     |.|:                ||    |.:::..:.:|
  Rat    74 VKTYSVSYTLEDLNYHFKFFAH-----NQWKTQEVGMFSLLKHSGKGFF----ELLFSHCRSLF- 128

  Fly   113 NDGVRREILRPGKAQFDLIIVDIWKYDAF-YSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSY 176
            .|....|.|:  ::.||.:.:|  .:|.. ..||.||..|.:..:.......:||....|||.||
  Rat   129 KDKKLVEYLK--QSSFDAVFLD--PFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSY 189

  Fly   177 LQSPSSYLYNLDTFGGRVAHVVEVAISWFNW-HWRYEQKHEALYKKYFPKIAETKPLSEISQ--- 237
            :....|...:..||..||            | |..|.:  |..:..||.|.| .:..||:.|
  Rat   190 VPRILSKFTDTMTFKERV------------WNHLSYMK--ERAFCPYFFKTA-VEIASEVLQTPV 239

  Fly   238 -------DIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFS 295
                   .:::.:....|.|..|||.:||::.:||::. .|.|.|:::.|.::..|||||::.||
  Rat   240 TMRDLFSPVSIWMFRTDFVLEFPRPVMPNMVYIGGINC-HQGKPLSKEFEAYVNASGEHGIVVFS 303

  Fly   296 LGTNVRTKNMVDDRKRI-LIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKL 359
            ||:.|   :.:.::|.: :.||.|.:||.|||::......::..|.::.|||||.|||.|||.:.
  Rat   304 LGSMV---SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARA 365

  Fly   360 FITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTE 424
            ||||.|.....|.|..|.||:.:|.|.||..|...::..|..::||..:||:|:|:..:..::..
  Rat   366 FITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINN 430

  Fly   425 KRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLV 489
            |.::.......:.::|:|::||:.||:|..||:|||||||:|.|...|:::.:|||||:|.:|.:
  Rat   431 KSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAI 495

  Fly   490 ILLVIIAILLIIVFSVCKIS--KNISTRLVVKKQRKQK 525
            :|.|:     .||:..|...  |....:..|||..|.|
  Rat   496 VLTVV-----FIVYKSCAYGCRKCFGGKGRVKKSHKSK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	Glycosyltransferase_GTB-type	33..484	CDD:471961	147/486 (30%)
Ugt1a8	NP_787040.2	UDPGT	26..521	CDD:278624	159/535 (30%)