DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35E1 and F10D2.8

DIOPT Version :9

Sequence 1:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001309630.1	Gene:	F10D2.8 / 266913	WormBaseID:	WBGene00017334	Length:	494	Species:	Caenorhabditis elegans

Alignment Length:	547	Identity:	126/547 - (23%)
Similarity:	215/547 - (39%)	Gaps:	95/547 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDIYV 72
            :|:||......|....|...|:..|||..........|...||.:|..:| ...|..:|:
Worm     4 FLVILSLIYSTYSYNFLVFCPLFGHSHTKFFATIADALTDAGHNVTFFTP-TIVEKYRNV----- 62

  Fly    73 PEVLNSFDELLK---QMTTPKNTWEFFD--ATNEFVYNITKD-VFNNDGVRREILRPGKAQFDLI 131
                 |:.:|.|   .|..||...|:.:  .:.:|....|:| .|.|.|..           ||.
Worm    63 -----SYTKLTKDVVHMDAPKKLMEYGEQMESADFSRFWTEDSSFYNVGAA-----------DLY 111

  Fly   132 IVDIWKYDAFYSLAAYFE----APIIGLAPCGIDWKIDEMVGN---PSPMSYLQSPSSYLYNL-- 187
            ...|.....|.||..|..    .|.:.|..   |..:.:.:|.   ||.:|.:.||.....:|
Worm   112 RCSIRLNGLFKSLMDYLNIKTFIPSLSLTH---DVYLSKAIGEPVMPSVVSDVCSPFGDKLSLLE 173

  Fly   188 DTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDIALVLVNQHFTLGP 252
            ..|.......:::.:.:        ..|..|...|......|     |..:.:.:.:|.:..|..
Worm   174 RAFNAFAVPYIDIVLGY--------PVHNTLSAPYTEIDIRT-----IEPEASFLFLNSNPFLDF 225

  Fly   253 PRPYVPNVIEVGGMHID-EQPKALAQD--------------LEDFIQGSGEHGVIYFSLGTNVRT 302
            |||.:...:|:||:.:| .|.|:...|              |..|       |.::||
Worm   226 PRPTLTKTVEIGGITVDLNQLKSQQLDSKWSDILNLREKTMLVSF-------GSVFFS------- 276

  Fly   303 KNMVDDRKRILIEAFGSLPQ-RVLWKFEDEELQDIP---SNVLVRKWLPQQDLLAHPKVKLFITH 363
            |:|..:.|:::..:...... ..:||:|..:::|..   .|:...||:||..|||:.::..|.||
Worm   277 KDMPLENKKVIANSMTEFKNVTFIWKYEGNDIEDFARGIQNIHFVKWVPQTALLANRRLSAFFTH 341

  Fly   364 GGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDM-TSDELKATILQLLTEKRF 427
            .|:.|..|..:.|||.:..|.|.||..|...:.:|...:.|:.:|: .|.::......:|.:..:
Worm   342 AGLGSINEVSYLGKPSILCPLFADQMRNAKMLVRHNGSIELSKYDLGNSKKIIEAFQAILFDSSY 406

  Fly   428 EVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILL 492
            ...|:....:..:||:||.:..|....:..|....|.:....||:||..:..||| .|:.:::|.
Worm   407 AENAQKLAEQLENQPIKPEKMMVKHAEFAARFGRLPSLDPYSRKMSFVEYFLLDV-ATICVLVLA 470

  Fly   493 VIIAILLIIVFSVCKISKNISTRLVVK 519
            .::.:|..:|..:|:       |.:||
Worm   471 CVVFVLTRVVQFLCR-------RFLVK 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	110/487 (23%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	111/485 (23%)
F10D2.8	NP_001309630.1	UDPGT	29..492	CDD:278624	119/522 (23%)
F10D2.8	NP_001309630.1	Glycosyltransferase_GTB_type	<215..461	CDD:299143	64/259 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	193	1.000	Inparanoid score	I2536
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860