DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35E1 and ugt-52

DIOPT Version :9

Sequence 1:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_499988.1	Gene:	ugt-52 / 176904	WormBaseID:	WBGene00018931	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	560	Identity:	123/560 - (21%)
Similarity:	233/560 - (41%)	Gaps:	97/560 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDI 70
            |||:::|                ..||..:..:|  :::|...||.:..:....:.....|..::
Worm    35 LFYILLL----------------GKSHIDFTDSL--IESLVENGHTVDLIIARMNSHVKSNGTNM 81

  Fly    71 YVPEVLNSFDE---------LLKQMTTPKNTWEFFDATNEFVYNITKDVFNNDGVRREILRPGKA 126
            ...:....|.|         ||......:.||      ||..|.:  |:..      ::...|.:
Worm    82 VTRKYTYGFQEESPWNKAPHLLNPFKGRERTW------NEHTYYM--DIVT------DLCEIGLS 132

  Fly   127 QFDL-IIVDIWKYDAFYSLAAYFEAPIIGLAP----CGID----WKIDEMVGNPS-PMSYLQSPS 181
            ...| ..:...|||             ||:|.    ||:.    :||..:|...| |:...||.:
Worm   133 DAGLHAFISSQKYD-------------IGIATEYENCGVALMKYYKIPSIVSVSSLPILDRQSLA 184

  Fly   182 SYLYNLDTFGGRVAHVVEVAISW------FNW-HWR-----YEQKHEA-LYKKYFPKIAETKPLS 233
            :.:.|.......:....::...|      .|| |..     |.:||:: :.||:   :.|....|
Worm   185 AGMPNSPAVTQAIFEAEDLTTYWGKFRNFLNWAHITLIINPYCEKHQSEVIKKH---LGENFDTS 246

  Fly   234 EISQDIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFI-QGSGEHGVIYFSLG 297
            .:.:.:.|..||.:..:..||.....:..:||:::.:....|.:::|..| |....:|::.|..|
Worm   247 NLIESLDLAFVNSNELIETPRVSSHKIKYIGGINLKKSKDRLDEEVEKVITQKPIGNGIVVFCFG 311

  Fly   298 TNVRTKNMVDDRKRILIEAFGSLPQ-RVLWKFE----DEELQDIPSNVLVRKWLPQQDLLAHPKV 357
            |.|.:.....:.:|...:||...|. ..:||:|    ||::....:|:.:.|||||.|||...:.
Worm   312 TQVPSSLFPIEVRRAFAQAFRHFPDFTFVWKYEMQDGDEQIFANTTNLRLLKWLPQTDLLNDART 376

  Fly   358 KLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLL 422
            |.||:|.|:.|.:||.:.|.|:|.:|.|.||..|.......|....|:...:|:..:...:..:|
Worm   377 KAFISHVGLNSYLESSYAGVPILAVPLFADQPHNAFSGMSIGTTYMLDKTRLTTPNIVKGLEAVL 441

  Fly   423 TEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLR----HKGAPHMRVAGRKLSFFTHHSLDVL 483
            .:..:.:.|:.......::|..|.:..|.|..:..|    |:   ::.:.|:.:|.|.::.||::
Worm   442 YDSSYTLNAKRISKMLHERPNPPKKIFVEWIEFASRNPLLHR---NLNLIGQNMSVFEYYCLDII 503

  Fly   484 GTVLLVILLVIIAILLIIVFSVCKISKNISTRLVVKKQRK 523
            ...:| :|.::|::..:....|.::.:.:   ..:.|:||
Worm   504 SFCIL-LLSIVISVFYLGTGWVSRMGRRV---FGILKKRK 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	111/496 (22%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	110/492 (22%)
ugt-52	NP_499988.1	UDPGT	53..537	CDD:278624	113/520 (22%)
ugt-52	NP_499988.1	Glycosyltransferase_GTB_type	<231..517	CDD:299143	73/292 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810