Protein Alignment Ugt303A1 and Ugt1a6a

DIOPT Version :9

• Sequence 1: NP_001262470.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 545
• Identity: 139/545 - (25%)
• Similarity: 245/545 - (44%)
• Gaps: 101/545 - (18%)

  Fly     8 AGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIE 72
            ||.|..||...:|..||.....        .||.:|.:...:.:|.:|||.:.::
Mouse    13 AGFLFLVLWASVLGDKLLVVPQ--------DGSHWLSMKEIVEHLSERGHDIMVL---------- 59

  Fly    73 GVHHIRVPKLDMLM--------KIL-----LDFEYDTDLTKWTEAQF---------LSEY----- 110
                  ||::::|:        ||.     |: |..|....:....|         |.||
Mouse    60 ------VPEVNLLLGESKYYRRKIFSVTYSLE-ELQTRFRTFGNNHFLPGASLMGPLREYRNNMI 117

  Fly   111 -----FYNCSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYG---------FSQHFNAPLLG 161
                 |.||          |.||::::   :|..|..:..|||:.         .:::.|.|
Mouse   118 VVDMFFSNC----------QSLLKDSA---TLSFLRENKFDALFTDPAMPCGVILAEYLNLP--- 166

  Fly   162 VAAY---GSSWNIDFLVGNS-APSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQ 222
             :.|   |...:::.::|.| :|..|.|.....::..:...::..|.|....|..:...:|...:
Mouse   167 -SVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYE 230

  Fly   223 I---DLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAEL 284
            |   ||.|:..  :..|:|    :.||.|:...|.....|..:||::.:.|::..:|. .|..|.
Mouse   231 IIASDLLKRDV--SLPSLH----QNSLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKG-KLTQEF 288

  Fly   285 KKILD-EAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFART 348
            :..:: ..|||::.||:|..:.:  :|......:::|..::.|.|:|:.......|.::|.....
Mouse   289 EAYVNASGEHGIVVFSLGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVK 351

  Fly   349 WFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNL 413
            |.||..:|.||..:.||||:|...:.|.:...||::.:|||.||..|.||||..|....|:...:
Mouse   352 WLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEM 416

  Fly   414 FRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSL 478
            ..|::..|::.::.|.|||.|...||....|:|:..:|.|::|.||::|||||.|:|.|..:::.
Mouse   417 TADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTW 481

  Fly   479 MQYYNVDVVSVLFGRIGLSAIIVIF 503
            .||:::||:..|.. |.|:.:.::|
Mouse   482 YQYHSLDVIGFLLA-IVLTVVFIVF 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	117/487 (24%)
		UDPGT	39..507	CDD:278624	131/514 (25%)
Ugt1a6a	NP_659545.2	egt	15..503	CDD:223071	136/539 (25%)
		UDPGT	27..522	CDD:278624	133/531 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840689
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.690