Protein Alignment Ugt303A1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 497
• Identity: 122/497 - (24%)
• Similarity: 238/497 - (47%)
• Gaps: 52/497 - (10%)

  Fly    39 GSSYLLITPFLRNLVQRGHQLTL--------ISAVTIMPHIE-GVHHIRVPKLDMLMKILLDF-- 92
            ||.:|.:...:..|:::.|.:|:        |:..:|.|.:. .::.:...| :.:..::.||
Mouse    30 GSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSISPSLTFEIYPVPFGK-EKIESVIKDFVL 93

  Fly    93 ----EYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQE-LLRN-------ASAKYSLIILEASHN 145
                ...:..|.||   |..|......:|.|...|:.: :|:|       ...|:.:::     :
Mouse    94 TWLENRPSPSTIWT---FYKEMAKVIEEFHLVSRGICDGVLKNEKLMSKLQKEKFEVLL-----S 150

  Fly   146 DALYG----FSQHFNAPLLGVAAYGSSWNIDFLVGN-SAPSVYEPMSALGYTSGLNLIEKWHNLI 205
            |.::.    .:.....|.:....:..:..::...|. ..|..|.|......|..::..::..|.|
Mouse   151 DPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFI 215

  Fly   206 -YITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVA 269
             |..::.:.|.   |.:|.|.|.....|..|::.:...:..:.|:..::.....|..:||...|.
Mouse   216 SYRMQDYMFET---LWKQWDSYYTKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVG 277

  Fly   270 GMHLDEKP-YPLDAELKKILD-EAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIW-- 330
            |:|.  || .||..|:::.:. ..|||::.||:|..:.:  |.......::.|.||:.|:|:|
Mouse   278 GLHC--KPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKN--LTDEKANLIASALAQIPQKVLWRY 338

  Fly   331 KTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQN 395
            |...|:.:..:..:|  .|.||..:|.||..:.||||.|...:.|::::.:|::.:|:|.||..|
Mouse   339 KGKIPDTLGSNTRLF--DWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDN 401

  Fly   396 TKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYI 460
            ...|:..|.|.:::...:...:::.|:..::...|||.||..||:..||||:..:|.|::|.|::
Mouse   402 IAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFV 466

  Fly   461 LRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVI 502
            :|||||.|:|:|..::|..||:::||:..|...:. |||:::
Mouse   467 MRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVA-SAILLV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	107/458 (23%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	122/497 (25%)