Protein Alignment Ugt303A1 and ugt2a4

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001170804.2
• Gene: ugt2a4 / 791613
• ZFINID: ZDB-GENE-080721-23
• Length: 533
• Species: Danio rerio
• Alignment Length: 554
• Identity: 153/554 - (27%)
• Similarity: 257/554 - (46%)
• Gaps: 96/554 - (17%)

  Fly     1 MFSGPGIAGLLLTVLLFG---------LLCP-KLTNAENILAVFSYTFGSSYLLITPFLRNLVQR 55
            |.||    .||:.:||.|         |:.| :.::..|:.|:               :..||.|
Zfish     1 MTSG----ALLVCLLLCGVDVGWSGRVLVMPGEYSHWHNMRAI---------------IEALVDR 46

  Fly    56 GHQLTLI--SAVTIMPHIEGV---HHIRVPKLDM--LMKILLDFEY----DTDLTKWTEAQFLSE 109
            .|.:|::  |:...:||.:..   :|:....:|.  ...|..||.:    :|| :|......:..
Zfish    47 NHSVTVLVSSSSPTVPHTQKARFDYHVFKVNMDKEEAKVIWSDFTHLWMKETD-SKLERGFLIWR 110

  Fly   110 YFYNCSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYG---------FSQHFNAPLLGVAAY 165
            ...|..:...:  ..:.||:|...   |.:|..||.|.|:.         .:|..|.|.:.....
Zfish   111 VMSNFRRLAAD--VCRSLLQNDDL---LQMLGESHYDVLFSDPMMPCSDLMAQTLNIPQVISLRL 170

  Fly   166 GSSWNIDFLVGN-SAPSVYEPMSAL--GYTSGLNLIEKWHNL----IYITEERL-----VERFIY 218
            ..::..:.:.|. .||..|.|..||  ..|..::.:|:..|:    |:.|..||     |:|
Zfish   171 TFAYTFERMCGQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYFIHTTVFRLNTMLTVDR--- 232

  Fly   219 LPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKP-YPLDA 282
                  ||.: ..|..|::.:...:..:.||..::.....|...||...|.|:|.  || .||..
Zfish   233 ------LYTE-IRGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHC--KPAKPLSK 288

  Fly   283 ELKKILDEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIW----KTDYPEMVNQSR 342
            |:::.:..: :|||:.||:|..:.:  |......:::.|..|:.|:|:|    ||  ||.:..:.
Zfish   289 EMEEFVQSSGDHGVVVFSLGSMIKN--LTSERANTIAAALGQIPQKVVWRYSGKT--PETLAPNT 349

  Fly   343 NVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARK 407
            .::  .|.||..:|.||..|.||||.|...|.|::::.||::.:|||.||..|...|:..|.|..
Zfish   350 KIY--DWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVV 412

  Fly   408 LDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIA 472
            ||...|...::|.|::.::.|.|||.:...||:..|||||..:|.|::|.|:::|:|||.|:|:.
Zfish   413 LDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQ 477

  Fly   473 EQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGW 506
            ..|:|..||:.:||.:.|   :.::|:|. || |
Zfish   478 AHELSWYQYHCLDVAAFL---LSIAALIT-FL-W 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	126/476 (26%)
ugt2a4	NP_001170804.2	UDPGT	21..520	CDD:278624	145/530 (27%)