DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303A1 and ugt5g1

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001107914.1	Gene:	ugt5g1 / 570913	ZFINID:	ZDB-GENE-080305-10	Length:	528	Species:	Danio rerio

Alignment Length:	535	Identity:	138/535 - (25%)
Similarity:	248/535 - (46%)	Gaps:	85/535 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLI-------------- 62
            ||.||..:.|   .:..||| ||... ||.::.:...||.|...||..|::
Zfish    11 LTCLLSVVCC---CHGGNIL-VFPED-GSHWVNMQVILRKLHTHGHSFTVVRSSKSWYIHENSAL 70

  Fly    63 -SAVTIMP-HIEGV----------HHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYN-- 113
             :.:|:.| ..|.|          ..:.:.|:..|::.   ||...|:|.      :.:.|:|
Zfish    71 YNTITVNPVETEDVGQDYFNMLLDRSLALQKMSPLVRF---FEQQKDITT------VLKVFHNGV 126

  Fly   114 --CSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVG 176
              ....:|:|..:.:.||  .||:.|::.:.:....:. .:.....|::        :|:.:|..
Zfish   127 LRMVSAMLDDAELVKSLR--EAKFDLLLTDPAFPAGVL-VANFLQLPMV--------YNVRWLNA 180

  Fly   177 NSA-------PSVYEPMSALGYTS----GLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHF 230
            ..|       |..|.||    |.|    .::.:::..|.:......|.||::.:|...:|.::||
Zfish   181 GDAHMQTAPSPPSYVPM----YNSLLHDQMSFLQRVENFLRYLCSLLQERYVIVPIYRELLERHF 241

  Fly   231 PGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKP---YPLDAELKKILDEAE 292
            |.. :.:..:::...:.|:...|.....|..:|||:.:.|...  ||   .|:|.| :.:....|
Zfish   242 PPG-SDLLSMQQSADIWLMRMDFVFDFPRPTMPNIIYMGGFQC--KPAQALPVDLE-EFMQSSGE 302

  Fly   293 HGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILN 357
            |||::.|:|..:  ..||..:..:::.|||::.|:|:|:...........|.....||||..:|.
Zfish   303 HGVVFMSLGAMV--GALPRTITEAIASAFAKIPQKVMWRYHGERPSTLGNNTLLLEWFPQNDLLG 365

  Fly   358 HPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAI 422
            ||..:.|::|.|...:.|::::.||:|.:||.:|||.|..|::....||.|....|...|.:..:
Zfish   366 HPKTRAFVSHGGTNGIYEAIYHGVPVLALPLLFDQFDNVMRLQVRNAARVLQVATLTSQEFLEGL 430

  Fly   423 EDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVV 487
            :|::.|..|:.:.|.:|:...|||:|.:|:|.:|.||::|||||.|:|.....::...|:::||:
Zfish   431 KDVLENPLYRSSIRKMSELHRDQPISPLDSATFWIEYVMRHKGAAHLRSEANNLAWYSYHSLDVL 495

  Fly   488 SVLFGRIGLSAIIVI 502
                  :.|.||.||
Zfish   496 ------VFLLAIAVI 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	120/482 (25%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	128/508 (25%)
ugt5g1	NP_001107914.1	UDPGT	24..526	CDD:278624	133/519 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.790