Protein Alignment Ugt303A1 and ugt2a2

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001018306.2
• Gene: ugt2a2 / 553952
• ZFINID: ZDB-GENE-080721-21
• Length: 534
• Species: Danio rerio
• Alignment Length: 520
• Identity: 139/520 - (26%)
• Similarity: 243/520 - (46%)
• Gaps: 68/520 - (13%)

  Fly    30 ILAVFSYTFGSSYLLIT------PFLRN----LVQRGHQLTLISAVTIMPHIEGVHHIR------ 78
            ::.:||:|...:.|::.      ..:||    |:.|.|.:|:: ..:..|.|......|
Zfish    13 LIFIFSFTHAGNVLVLPGEYSHWQNMRNVVDELLNRNHTVTVL-VCSASPTINFTQQERFQYLVF 76

  Fly    79 -VP----KLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPG---------VQELLR 129
             ||    :||...:.|:..        ||  |..|......:..::|..|         ...:||
Zfish    77 EVPLSAQELDGASEELIHI--------WT--QHPSPNRLQTALQIIELLGRVRVMHRAMCDSMLR 131

  Fly   130 NAS--AKYSLIILEASHNDALYG----FSQHFNAPLLGVAAYGSSWNIDFLVGN-SAPSVYEPMS 187
            |.:  |:.|.:..:...||.::.    .::....||:........:.::.:.|. .||..:.|::
Zfish   132 NDALIAQLSALKFDVLFNDPMFMCADLLAEMLGLPLVLSVRISPGFCLERMCGQMPAPPSFVPIT 196

  Fly   188 ALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQH 252
            ....|..:..:|:..|:| ......|..:|.....:|.|.....|..|::.:...:..:.||..:
Zfish   197 QTVLTDRMCFMERVQNMI-ANIVFSVSFYIVAWISLDSYYTDVLGKPTTMCETMGKADIWLIRTY 260

  Fly   253 FTMGRVRSNVPNIVEVAGMHLDEKP-YPLDAELKKILDEA-EHGVIYFSMGLQLLDHWLPPGMRA 315
            :.....|...||...|.|:|.  || .||..|:::.:..: :|||:.||:|..:.:  |......
Zfish   261 WDFEYPRPFPPNFKFVGGLHC--KPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIKN--LTSERAN 321

  Fly   316 SMSDAFAQLKQQVIW----KTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIES 376
            :::.|..|:.|:|:|    ||  ||.:..:..::  .|.||..:|.||..|.||||.|...|.|:
Zfish   322 TIAAALGQIPQKVVWRYSGKT--PETLAPNTKIY--DWIPQNDLLGHPKTKAFITHGGTNGLYEA 382

  Fly   377 VHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQR 441
            :::.||::.:|||.||..|...|:..|.|..||...|...::|.|::.::.|.|||.:...||:.
Zfish   383 IYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRI 447

  Fly   442 FHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGW 506
            .|||||..:|.|::|.|:::|:|||.|:|:...|:|..||:.:||.:.|   :.::|:|. || |
Zfish   448 HHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFL---LSIAALIT-FL-W 507

  Fly   507  506
            Zfish   508  507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	122/477 (26%)
ugt2a2	NP_001018306.2	UDPGT	23..521	CDD:278624	136/510 (27%)