DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303A1 and Ugt35C1

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001097744.1	Gene:	Ugt35C1 / 53507	FlyBaseID:	FBgn0040256	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	513	Identity:	185/513 - (36%)
Similarity:	300/513 - (58%)	Gaps:	28/513 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLTV--LLFGLLCPKLTNAEN--ILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISA-----VT 66
            ||||  ::|..|..|...:|:  |||...:...|.|:.:..:|:.|..:|||:|:|:|     ..
  Fly     3 LLTVIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFKNKETP 67

  Fly    67 IMPHIEGV--HHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFV---LEDPGVQE 126
            .|..||.:  |......:.:|...||          |   |.|:...|..:||:   :||.|||.
  Fly    68 NMRFIEALKAHEFADEMMSLLNVPLL----------W---QQLNAMDYILNKFIDVTMEDEGVQR 119

  Fly   127 LLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMSALGY 191
            || |:...:.|::.|..|.:.:|.|:|||||.|:|.:::|:...||...||.:|..|.|:.....
  Fly   120 LL-NSGETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTSPR 183

  Fly   192 TSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMG 256
            |..:..:|:..|...:..|.:...|::||...::||::||.|..::.::...|||:|:.|||::.
  Fly   184 TDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLS 248

  Fly   257 RVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAF 321
            ..|..:||::||.|||:..||.||..::|:.::.:.|||||||||..:....||...|.::...|
  Fly   249 YPRPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETRDTLLKTF 313

  Fly   322 AQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCI 386
            |:|||:|:||.:..:|..:..||..:.|:||..||.||||||||:|.||||..|||::..|:|.:
  Fly   314 AKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGL 378

  Fly   387 PLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMD 451
            |.||||..|.:|.:::|....||..||.::::..||:.|:.:.||.:.:..:|:|:.|||.||:|
  Fly   379 PCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVD 443

  Fly   452 TAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLV 509
            .|:|||||::||.||.|:|...::::.:|..::|.::|:.....|.|::::.|..||:
  Fly   444 RAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSCKLL 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	166/450 (37%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	172/477 (36%)
Ugt35C1	NP_001097744.1	egt	1..470	CDD:223071	177/480 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	10	9.870