Protein Alignment Ugt303A1 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 144/545 - (26%)
• Similarity: 242/545 - (44%)
• Gaps: 69/545 - (12%)

  Fly     6 GIAGLL--LTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIM 68
            ||.|.|  |:.||. ||| .|..||....:.....||.:|.:...:|.|..||||     ||.:.
  Rat     2 GIQGFLQKLSGLLL-LLC-ALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQ-----AVVLA 59

  Fly    69 PHIEGVHHIRVPKLDMLMKILLDF---EYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQELLRN 130
            |.:  ..||:......|....:.:   ||...|....:..|.:|:   ..|.||:.   ...:.|
  Rat    60 PEV--TVHIKEEDFFTLQTYPVPYTKEEYRHHLLGHLQNFFETEF---SLKLVLQR---MAAVNN 116

  Fly   131 ASAKYSLIILEASHNDALY------GFSQHFNAPLLGVAAYGSSW--------------NIDFLV 175
            .|..|........||.||.      .|......|.....|..:.:              .::|..
  Rat   117 VSTFYVRSCRGLLHNTALIQSLNSSSFDVVLTDPFFPCGAVLAMYLRVPAVFFLQSMLCELEFEA 181

  Fly   176 GNSA-PSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPR---------QIDLYKQHF 230
            .||. ||.|.|......:..::.:::..|::|...      ::||..         ..||.::.
  Rat   182 TNSPNPSSYIPRLLTLNSDHMSFLDRVKNMLYPVP------WMYLCHVNYGSLARLASDLLQRE- 239

  Fly   231 PGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILD-EAEHG 294
                .|:.::.|..|:.|:.:.|.....|..:||:|.:.|::...:. ||..|.:..:: ..|||
  Rat   240 ----VSVVEILRHASVWLLRKDFVFYYPRPFMPNMVFIGGINCANRK-PLSQEFEAYVNASGEHG 299

  Fly   295 VIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHP 359
            ::.||:|..:.:  :|......:::|..::.|.|:|:.......|.::|.....|.||..:|.||
  Rat   300 IVVFSLGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHP 362

  Fly   360 NVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIED 424
            ..:.||||:|...:.|.:...||::.:|||.||..|.||||..|....|:...:..|::..|::.
  Rat   363 KARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKT 427

  Fly   425 LVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSV 489
            ::.|.|||.|...||....|:|:..:|.|::|.||::|||||.|:|.|..:::..||:::||:..
  Rat   428 VINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGF 492

  Fly   490 LFGRIGLSAIIVIFLGWKLVSLATR 514
            |...:    :.|:|:.:|..:...|
  Rat   493 LLAIV----LTVVFIVYKSCAYGCR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	118/472 (25%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	131/519 (25%)