Protein Alignment Ugt303A1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_958826.1
• Gene: Ugt1a2 / 396527
• RGDID: 1549741
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 142/549 - (25%)
• Similarity: 237/549 - (43%)
• Gaps: 84/549 - (15%)

  Fly     6 GIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPH 70
            |::||||      ||| .|..||....:.....||.:|.:...:|.|..||||     ||.:.|.
  Rat    11 GLSGLLL------LLC-ALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQ-----AVVLAPE 63

  Fly    71 IEGVHHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQELLRNASAKY 135
            :. ||          ||....|...|....:|:.::..|...|..|.......|:......::..
  Rat    64 VT-VH----------MKGEDFFTLQTYAFPYTKEEYQREILGNAKKGFEPQHFVKTFFETMASIK 117

  Fly   136 SLIILEAS------HNDALYGFSQHFNA---------PLLGVAAYGSSW--------------NI 171
            ....|.|:      ||..|.   |..|:         |:....|..:.:              .|
  Rat   118 KFFDLYANSCAALLHNKTLI---QQLNSSSFDVVLTDPVFPCGALLAKYLQIPAVFFLRSVPCGI 179

  Fly   172 DFLVGN-SAPSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATT 235
            |:.... ..||.|.|......:..:..:::..|::|    .|..::|       .:....|..:.
  Rat   180 DYEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLY----PLTLKYI-------CHLSITPYESL 233

  Fly   236 SIHDLRRRFSLVLINQH---------FTMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILD-E 290
            :...|:|..|||.:..|         |.....|..:||:|.:.|::...|. ||..|.:..:: .
  Rat   234 ASELLQREMSLVEVLSHASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIKK-PLSQEFEAYVNAS 297

  Fly   291 AEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAI 355
            .|||::.||:|..:.:  :|......:::|..::.|.|:|:.......|.::|.....|.||..:
  Rat   298 GEHGIVVFSLGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDL 360

  Fly   356 LNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVL 420
            |.||..:.||||:|...:.|.:...||::.:|||.||..|.||||..|....|:...:..|::..
  Rat   361 LGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLEN 425

  Fly   421 AIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVD 485
            |::.::.|.|||.|...||....|:|:..:|.|::|.||::|||||.|:|.|..:::..||:::|
  Rat   426 ALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLD 490

  Fly   486 VVSVLFGRIGLSAIIVIFLGWKLVSLATR 514
            |:..|...:    :.|:|:.:|..:...|
  Rat   491 VIGFLLAIV----LTVVFIVYKSCAYGCR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	118/478 (25%)
Ugt1a2	NP_958826.1	UDPGT	28..524	CDD:278624	131/525 (25%)