Protein Alignment Ugt303A1 and Ugt1a6b

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 545
• Identity: 140/545 - (25%)
• Similarity: 246/545 - (45%)
• Gaps: 101/545 - (18%)

  Fly     8 AGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIE 72
            ||.|..||...:|..||.....        .||.:|.:...:.:|.:|||.:.::
Mouse    13 AGFLFLVLWASVLGDKLLVVPQ--------DGSHWLSMKEIVEHLSERGHDIVVL---------- 59

  Fly    73 GVHHIRVPKLDMLM--------KIL-----LDFEYDTDLTKWTEAQF---------LSEY----- 110
                  ||::::|:        ||.     |: |..|....:...||         |.||
Mouse    60 ------VPEVNLLLGESKYYRRKIFSVPYSLE-ELQTRFRTFGRNQFVPGAPLMGPLREYRNSML 117

  Fly   111 -----FYNCSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYG---------FSQHFNAPLLG 161
                 |.||          |.||::::   :|..|..:..|||:.         .:::.|.|
Mouse   118 TLEMFFSNC----------QSLLKDSA---TLSFLRENKFDALFTDPAMPCGVILAEYLNLP--- 166

  Fly   162 VAAY---GSSWNIDFLVGNS-APSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQ 222
             :.|   |...:::.::|.| :|..|.|.....::..:...::..|.|....|..:...:|...:
Mouse   167 -SVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYE 230

  Fly   223 I---DLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAEL 284
            |   ||.|:..  :..|:|    :.||.|:...|.....|..:||::.:.|::..:|. .|..|.
Mouse   231 IIVTDLLKRDV--SLPSLH----QNSLWLLRYDFVFEYPRPIMPNMIFIGGINCKKKG-KLTQEF 288

  Fly   285 KKILD-EAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFART 348
            :..:: ..|||::.||:|..:.:  :|......:::|..::.|.|:|:.......|.::|.....
Mouse   289 EAYVNASGEHGIVVFSLGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVK 351

  Fly   349 WFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNL 413
            |.||..:|.||..:.||||:|...:.|.:...||::.:|||.||..|.||||..|....|:...:
Mouse   352 WLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEM 416

  Fly   414 FRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSL 478
            ..|::..|::.::.|.|||.|...||....|:|:..:|.|::|.||::|||||.|:|.|..:::.
Mouse   417 TADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTW 481

  Fly   479 MQYYNVDVVSVLFGRIGLSAIIVIF 503
            .||:::||:..|.. |.|:.:.::|
Mouse   482 YQYHSLDVIGFLLA-IVLTVVFIVF 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	118/487 (24%)
Ugt1a6b	NP_958812.3	UDPGT	27..522	CDD:278624	134/531 (25%)