Protein Alignment Ugt303A1 and Ugt1a10

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_964003.2
• Gene: Ugt1a10 / 394430
• MGIID: 3580642
• Length: 530
• Species: Mus musculus
• Alignment Length: 538
• Identity: 147/538 - (27%)
• Similarity: 245/538 - (45%)
• Gaps: 87/538 - (16%)

  Fly    10 LLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIE-- 72
            |.|.|.|  ||...|..|..:|.|  ...||.:..:...:..|:||||::     |.::|.:.
Mouse    10 LPLCVCL--LLASGLVQAGRLLVV--PMDGSHWFDMQMVVEKLIQRGHEV-----VVVIPEVSWR 65

  Fly    73 ------------GVHHIRVPKLDMLMKILLDFEYDTDLTKWT------------EAQFLSEYFYN 113
                        .|.| .:..||.      :|:|.| .|:|.            .|:...|..::
Mouse    66 LGKSLNCTVKTYSVSH-TLEDLDR------EFKYFT-YTQWKTPEQSIRSFMTGSARGFFELMFS 122

  Fly   114 CSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFL---- 174
            .|:.:..|..:.|.|:..|.            ||:  |...|:...|.||.|.|..::.|.
Mouse   123 HSRGLFNDKKLVEYLKQRSF------------DAV--FLDPFDVCGLIVAKYLSLPSVIFARLSF 173

  Fly   175 -----VGNSAPSV--YEPMSALGYTSGLNLIEK-WHNLIYITEERLVERFIYLP----RQIDLYK 227
                 .|...||:  |.|.....||..:...|: |::.:||      |.:::.|    ..:::..
Mouse   174 CYYLEEGAQCPSLLSYVPRLFSKYTDTMTFKERVWNHYMYI------EDYVFCPYFFKTAVEIAS 232

  Fly   228 QHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMH-LDEKPYPLDAELKKILD-E 290
            :......| :.||....|:.|:...|.:...|..:||:|.|.||: |..|  ||..|.:..:: .
Mouse   233 EVLQTPVT-MTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFVGGMNCLQGK--PLSKEFEAYVNAS 294

  Fly   291 AEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAI 355
            .|||::.||:|..:.:  :|......:::|..::.|.|:|:.......|.::|.....|.||..:
Mouse   295 GEHGIVVFSLGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDL 357

  Fly   356 LNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVL 420
            |.||..:.||||:|...:.|.:...||::.:|||.||..|.||||..|....|:...:..|::..
Mouse   358 LGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLEN 422

  Fly   421 AIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVD 485
            |::.::.|.|||.|...||....|:|:..:|.|::|.||::|||||.|:|.|..:::..||:::|
Mouse   423 ALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLD 487

  Fly   486 VVSVLFGRIGLSAIIVIF 503
            |:..|.. |.|:.:.::|
Mouse   488 VIGFLLA-IVLTVVFIVF 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	126/482 (26%)
Ugt1a10	NP_964003.2	UDPGT	26..521	CDD:278624	139/520 (27%)