DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303A1 and ugt-39

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_504816.2	Gene:	ugt-39 / 3564933	WormBaseID:	WBGene00017329	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	552	Identity:	121/552 - (21%)
Similarity:	222/552 - (40%)	Gaps:	94/552 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLTVLLFG--------LLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVT 66
            |.:..|.||        :.||          :|:::....:..|..   :|...||.:|..:. |
Worm     4 LFILFLFFGNVSSFNFLVFCP----------LFAHSHSKFFATIAD---SLTDAGHNVTFFTP-T 54

  Fly    67 IMPHIEGVHHIRVPKLDMLMKILLDF-EYDTDLTK------WTEAQFLSEY---------FYNCS 115
            |:.....|.:.:..|..:.||..... ||...::.      |||....:|.         .||..
Worm    55 IVEKYRNVSYTKSTKDVVHMKPSKKLKEYGEQMSTGDFVRYWTEDSTATEIIPVVRIFQKMYNEQ 119

  Fly   116 KFVLED-PGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGV-----------AAYGSS 168
            ..|::| .|:...|:  ..|:.:||.||      |.:|.:   ||:..           .|:.:|
Worm   120 GTVMKDNVGILNELK--KRKFDVIIFEA------YIYSAY---PLMDYLEIPTFIPSVSVAHDTS 173

  Fly   169 WNIDFLVGNSA-PSVY-EPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHF- 230
            ..|:  :|... |||. :.:|..|  ..|::.|:..|...:.         |....|. |..|.
Worm   174 LAIE--IGEPVMPSVVSDCLSPFG--DKLSITERAFNAFMVP---------YFDFMIG-YPTHRS 224

  Fly   231 ---PGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDE---KPYPLDAELKKILD 289
               |.....|..:....|.|.:|.:..:...|..:...:::.|:.:|.   :...||....:||.
Worm   225 FKPPYNPIDIRSIVPEASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEILK 289

  Fly   290 EAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQ-QVIWKTD---YPEMVNQSRNVFARTWF 350
            ..|..:: .|.|..|....:|...:.::.:|..:.|. ..|||.:   ..|......|:....|.
Worm   290 LREKTML-VSFGSMLYSKDMPFKNKIALKNAMEKFKNVTFIWKYEDDSSDEFAKGIENIHFAKWV 353

  Fly   351 PQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFR 415
            ||.|:|....:..|:|||||.|:.|..:...|.:..|..:||.:|.|.:.:...:.:|...:|..
Worm   354 PQTALLADSRLSAFLTHAGLGSINELSYLGKPAILCPQLFDQMRNAKMLVRHNGSIELSKYDLGD 418

  Fly   416 DE-IVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLM 479
            .| ||.|.:.:::::||.:||..|:::..:||:...:..:...|:..|......:....::|:.:
Worm   419 SEKIVNAFQAILFDSSYAKNALKLAEQLENQPIKPKEMMVKHAEFAARFGRLPSLDPYSRKMTFI 483

  Fly   480 QYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSL 511
            :|:.:||.::..    :..|.|:|:..|:..:
Worm   484 EYFLIDVAAISM----VVLIAVVFVITKMFKI 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	107/480 (22%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	113/509 (22%)
ugt-39	NP_504816.2	Glycosyltransferase_GTB_type	12..503	CDD:299143	116/534 (22%)
ugt-39	NP_504816.2	UDPGT	29..521	CDD:278624	114/517 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	161	1.000	Domainoid score	I2438
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.900