DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303A1 and Ugt36F1

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	138/518 - (26%)
Similarity:	256/518 - (49%)	Gaps:	30/518 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIEGV 74
            ||...||..||.||..:|.:||.:|.:...|.:....|....|.:|||.:::.|...:...:...
  Fly     3 LLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANY 67

  Fly    75 HHIRVPKLDMLMKI--LLDFEYDTDLTKWTEAQ---------FLSEYFYNCSKFVLEDPGVQELL 128
            .......:.:|..|  |.:||     ::|....         .|.::.....|..|..|.:.:||
  Fly    68 TDYVFQGMPLLTDIVDLSNFE-----SEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLL 127

  Fly   129 RNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYG-SSWNIDFLVGNSAPSVYEPMSALGYT 192
            : :..:|.:|:||...||.:...:...|||::.:::.. ..|:.. .:|:...:...||:.|.||
  Fly   128 K-SPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYK-RMGSPFINPIMPMNFLPYT 190

  Fly   193 SGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGR 257
            ..::||::.:|..:......:...|..|....|..:.|......|:::.:..||:|||||:.:..
  Fly   191 DEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTG 255

  Fly   258 VRSNVPNIVEVAGMHLDE-KPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAF 321
            .|...||::||.|:.:.. ||.|  ..|..:||.:.:||||.|.|..:..:.||.|.|:::..:.
  Fly   256 PRPYAPNVIEVGGLQVGPIKPLP--QHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSI 318

  Fly   322 AQLKQQ---VIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPL 383
            :|||:.   :.||:.......|..|::...|.|||.:|.||.::.||:|.|||...|::|..||:
  Fly   319 SQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPM 383

  Fly   384 LCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMS 448
            |..|.:.|||.|:..:::.|....:||::...:.|...:. ::.:..:....|..|:.|..:|:.
  Fly   384 LVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIP 447

  Fly   449 AMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSL 511
            .:..|.||.|:::::.||.|::...:.::.:.|.::||  :||. :|:..::::.|. ||:.:
  Fly   448 PIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDV--LLFW-LGILFLLIVALR-KLIKI 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	118/454 (26%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	124/483 (26%)
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	124/479 (26%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	113/432 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454646
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890