DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303A1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	171/515 - (33%)
Similarity:	278/515 - (53%)	Gaps:	35/515 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLI------------SA 64
            :.:.|.|||  :......||.:..:...|.:|.:..|..:|:::||.:|.:            :.
  Fly    11 MLIFLIGLL--EFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTE 73

  Fly    65 VTIMPHIEGVHHIRVPKLDML-MKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQELL 128
            :.|.|..:...|.  ||.::. |:.:.||. :.:|. ||.....:|:.:       :||.|::|:
  Fly    74 IIISPSFDIPKHF--PKENIFSMQFVSDFN-NLELW-WTIGLMTTEHAF-------KDPKVKKLI 127

  Fly   129 RNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMSALGYTS 193
            .:....|.|:|:|...::|...|.:.||.|::.:...|.:.|||..:|...|....|...|.:|.
  Fly   128 ESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTD 192

  Fly   194 GLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGA----TTSIHDLRRRFSLVLINQHFT 254
            .:...::.:|......:.::.|::|||:...|.:::|.|:    ..::.||.|..||||||.|.:
  Fly   193 RMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRS 257

  Fly   255 MGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSD 319
            :...|.::|.:::|.|.|: :||..|..:|:..||.|.:||||||||..:....||....|.:..
  Fly   258 IDLPRPSMPGLIDVGGAHI-QKPKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILK 321

  Fly   320 AFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLL 384
            ||.|||||||||.:...:.:...||..:.|.||..||.||||||||||.|:....|.:::.||:|
  Fly   322 AFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPML 386

  Fly   385 CIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSA 449
            |:||:.||.:||.:..:.|.||.|.|..|..|::|..||.|:.:..|||:|.::||||.|.|:..
  Fly   387 CVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHP 451

  Fly   450 MDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLV 509
            :|.|.:|.|||:||:||.|::.....:.|.||..:||:..|.    |.|.:.|:|.|:::
  Fly   452 LDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLL----LGAFLAIWLPWRMI 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	153/455 (34%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	164/484 (34%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	161/484 (33%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	155/457 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860