Protein Alignment Ugt303A1 and Ugt2b10

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001178605.1
• Gene: Ugt2b10 / 305264
• RGDID: 1309989
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 137/551 - (24%)
• Similarity: 256/551 - (46%)
• Gaps: 101/551 - (18%)

  Fly     8 AGLLLTVL----LFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIM 68
            |.|||.:|    .||      :.....:.|:...| |.:|.:...|..|:::||::|::.....:
  Rat     7 ASLLLLLLQLSDFFG------SGTGGKVLVWPMEF-SHWLNLRVILDELLKKGHEVTVLRPSASL 64

  Fly    69 PHIEGVHHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFY-NCSKFVLEDPG--------- 123
            .:          ::|....|    |::|..|.::..: :.|:|: :..|::.|.|.
  Rat    65 SY----------EVDNTSAI----EFETYPTSYSLTE-VDEFFWESLRKYIYELPKQSFWGYFLM 114

  Fly   124 VQELLRNASAKYSLIILEASHNDALY------GF---------------SQHFNAPLLGVAAY-- 165
            .|||:...|..:..:..:...|..|.      ||               ::....||:....:
  Rat   115 FQELVWVDSDYFESLCKDVVFNKELMTKLQNSGFDVILADPFIPCGDLLAEILKIPLVYSLRFFP 179

  Fly   166 GSSWNIDFLVGNSAPSVYEPMSALGYTSGLNLIEKWHNLIYI----------TEERLVERFIYLP 220
            ||::. .:..|...|..|.|::....:..:..:|:..::||:          .|::..|
  Rat   180 GSTYE-KYSGGLPMPPSYVPIAMSELSDRMTFVERMKHMIYVLCFDFWFQAFNEKKWNE------ 237

  Fly   221 RQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHL-DEKPYPLDAEL 284
                ||.:.. |..|::.:...:..:.||..::.:......:||...|.|:|. ..||.|.:.|
  Rat   238 ----LYTEVL-GRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFVGGLHCRPAKPLPKEIE- 296

  Fly   285 KKILDEAEHGVIYFSMGL---QLLDHWLPPGMRASMSDA-FAQLKQQVIWKTD--YPEMVNQSRN 343
            ..:....||||:.||:|.   .|.:.      ||::..| .||:.|:|:|:.:  .||.:..:..
  Rat   297 DFVQSSGEHGVVVFSLGSMVGNLTEE------RANVIAAGLAQIPQKVLWRFEGKKPETLGSNTR 355

  Fly   344 VFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKL 408
            ::  .|.||..:|.||..:.||||.|...:.|::::.:|::.||||.||:.|...::..|.|.:|
  Rat   356 LY--KWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKTKGAAVRL 418

  Fly   409 DFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAE 473
            ||..:...::..|::.:..:.|||.||..||:..||||:..:|.|::|.|:::|||||.|:|:|.
  Rat   419 DFLTMSSTDLFTALKTITNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAA 483

  Fly   474 QEMSLMQYYNVDVVSVLFGRIGLSAIIVIFL 504
            .::|.:||:::||:..|...:    :.|:|:
  Rat   484 HDLSWVQYHSLDVIGFLLACV----VTVMFI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	116/488 (24%)
Ugt2b10	NP_001178605.1	UDPGT	26..529	CDD:278624	130/526 (25%)