Protein Alignment Ugt303A1 and Ugt2b37

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001007265.4
• Gene: Ugt2b37 / 29623
• RGDID: 3937
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 142/548 - (25%)
• Similarity: 241/548 - (43%)
• Gaps: 89/548 - (16%)

  Fly     4 GPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIM 68
            |..|..|||..:.|   |.:......:| |:...| |.::.|...|..||||||::|::.
  Rat     3 GKWIFALLLLQISF---CLRSAKCGKVL-VWPMEF-SHWMNIKTILDELVQRGHEVTVLK----- 57

  Fly    69 PHIEGVHHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFY-------------NCSKFVLE 120
               ...:::..||...      |.:::|..|..::.: |.:||.             .|..|
  Rat    58 ---PSAYYVLDPKKSP------DLKFETFPTSVSKDE-LEKYFIKLVDAWTYELQRDTCLSF--- 109

  Fly   121 DPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLL---GVAAYG----SSWNIDFLVGNS 178
            .|.:|.::...|..|..:..:|..|..|....|.....:|   .|||.|    ...:|.||....
  Rat   110 SPLLQNMMDEFSDYYLSVCKDAVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLR 174

  Fly   179 A---------------PSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERF---IYLPRQIDL 225
            |               |..|.|:...|....:..|::..|:|.:    |...|   ::..:..|.
  Rat   175 ASPGHKIEKSSGRFILPPSYVPVILSGLGGQMTFIDRVKNMICM----LYFDFWFHMFNAKNWDP 235

  Fly   226 YKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHL-DEKPYPLDAELKKILD 289
            :.....|..|::.:...:..:.||..::.:......:||:..:.|:.. ..||.|.|.| ..:..
  Rat   236 FYTEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCKPAKPLPKDIE-DFVQS 299

  Fly   290 EAEHGVIYFSMGLQLLDHWLPPGMRASMSD--------AFAQLKQQVIWKTD--YPEMVNQSRNV 344
            ..||||:.||:|          .|.:||::        |.||:.|:|:||.|  .|..:..:..|
  Rat   300 SGEHGVVVFSLG----------SMVSSMTEEKANAVAWALAQIPQKVLWKFDGKIPATLGPNTRV 354

  Fly   345 FARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLD 409
            :  .|.||..:|.||..|.|:||.|...:.|::::.:|::.||:|.:|..|...|...|.|..|:
  Rat   355 Y--KWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLN 417

  Fly   410 FKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQ 474
            .:.:.:.::..|:::::.|..||:||..||...|||||..:|.||:|.||::|||.|.|:|....
  Rat   418 IRTMSKSDLFNALKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLRPLGH 482

  Fly   475 EMSLMQYYNVDVVSVLFGRIGLSAIIVI 502
            .:...||:::||:..|...:.:.|.:.:
  Rat   483 NLPWYQYHSLDVIGFLLACLAVIAALAV 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	125/487 (26%)
Ugt2b37	NP_001007265.4	UDPGT	24..527	CDD:278624	135/524 (26%)