Protein Alignment Ugt303A1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 127/494 - (25%)
• Similarity: 225/494 - (45%)
• Gaps: 73/494 - (14%)

  Fly    40 SSYLLITPFLRNLVQRGHQLTLISAVTIMPHIEGVHHIRVPKLDMLMKILLDFE-----YDTD-- 97
            |.:|.:...|..|..|||::|::...:|:             :|......|.||     |:|:
  Rat    34 SHWLNLKTILEELAARGHEVTVLKYPSII-------------IDQSKLTPLQFENIPVLYETEVA 85

  Fly    98 -----------------LTKWTEAQFLSEYFYNCS-------KFVLEDPGVQELLRNASAKYSLI 138
                             |:.|..|:.|.::|...:       :..|.:..:...||:  |||.::
  Rat    86 ENHLNEIVNLAVNVIPNLSLWEAARTLQDFFLQLTGNFEDLCRSTLYNQTLMNKLRD--AKYDVM 148

  Fly   139 ILEASHNDALYG----FSQHFNAPLLGVAAYGSSWNIDFLVGN-SAPSVYEPMSALGYTSGLNLI 198
            :|     |.:..    .::....|.:....:...::::...|. ..|..|.|:.....|..:...
  Rat   149 VL-----DPVIPCGELVAEVLQIPFVNTLRFSMGYSMEKYCGQLPVPLSYVPVVMGELTDHMTFT 208

  Fly   199 EKWHNLIYITEERLVERFIYLPRQID--LYKQHFP---GATTSIHDLRRRFSLVLINQHFTMGRV 258
            |:..|::      |...|.:..:|.|  .:.|.:.   |..|:......:..:.||..::.:...
  Rat   209 ERVKNMM------LSLFFEFWLQQYDFAFWDQFYSKTLGRPTTFCKTVGKAEIWLIRTYWDIEFP 267

  Fly   259 RSNVPNIVEVAGMHLDEKP-YPLDAELKKILDEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAF 321
            |..:||...|.|:|.  || .||..||::.:..: ||||:.||:|..:.:  |.......::.|.
  Rat   268 RPYLPNFEFVGGLHC--KPAKPLPKELEEFVQSSGEHGVVVFSLGSMIKN--LTEEKANLIASAL 328

  Fly   322 AQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCI 386
            ||:.|:|:|:....:......|.....|.||..:|.||..:.||||.|...:.|::::.||::.|
  Rat   329 AQIPQKVLWRYSGKKPATLGPNTRILNWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGI 393

  Fly   387 PLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMD 451
            |:|.||..|...||..|.|.|:....:...:::.|:..::...|||.||..||:..||||:..:|
  Rat   394 PMFGDQPYNIAHMEAKGAAVKVAINTMTSADLLSALRAVINEPSYKENAMRLSRVHHDQPVKPLD 458

  Fly   452 TAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVL 490
            .|::|.|:::|||||.|:|:|..::|..||:::||:..|
  Rat   459 RAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	115/467 (25%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	127/494 (26%)