Protein Alignment Ugt303A1 and Ugt2b7

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_775445.2
• Gene: Ugt2b7 / 286989
• RGDID: 708417
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 139/540 - (25%)
• Similarity: 247/540 - (45%)
• Gaps: 80/540 - (14%)

  Fly     7 IAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLI---SAVTIM 68
            |:.|||..:.|   |.:..|...:| |:...: |.::.:...|..||||||::|::   |:|.:.
  Rat     6 ISALLLLQISF---CFRSGNCGKVL-VWPLEY-SHWMNLKIILDELVQRGHEVTVLRPSSSVFLD 65

  Fly    69 P-HIEGVHHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFV---------LEDPG 123
            | ...|:.:...|....      :.|.:...|:|..........|.|.::.         ..|..
  Rat    66 PKKASGLVYETFPTTSN------NDEVEKFFTQWVNTWTYDVPKYTCLRYYPSLNKMFGQFSDLW 124

  Fly   124 VQELLRNASAKYSLIILEASHNDALYG---------FSQHFNAPLLGVAAYGSSWNID-FLVGNS 178
            :|......|.|:.:..|:.|..|.:..         .::....|.:....:|..:.|: :..|..
  Rat   125 LQLCREVVSNKHLMAKLKESQFDVVLSDAVGPCGELIAEILQLPFVYSLRFGIGYGIEKYSAGQP 189

  Fly   179 APSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFP------------ 231
            .|..|.|:...|.:..:..:|:..|::.:         :|    .|.:.:.||
  Rat   190 FPPSYVPIILSGLSGQMTFMERVENMLCL---------LY----FDFWFESFPAKDWDPFFSEIL 241

  Fly   232 GATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLD-EKPYPLDAELKKILDEA---- 291
            |..|::.|..::..:.||..::.:...|.::|||..|.|:|.. .||.|     |::.|.|
  Rat   242 GRPTTMVDTMKKAEIWLIRSYWDLEFPRPSLPNIEFVGGLHCQPAKPLP-----KEMEDFAQSSG 301

  Fly   292 EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTD--YPEMVNQSRNVFARTWFPQRA 354
            ||||:.||:|..:.:  :......:::.|.||:.|:|.|:.:  .|:.:..:..||  .|.||..
  Rat   302 EHGVVVFSLGSMIRN--ITQERANTIASALAQIPQKVFWRFEGKKPDTLGPNTRVF--KWIPQND 362

  Fly   355 ILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIV 419
            :|.||..|.|:||.|...:.||:|:.:|::.||||.:|..|...|...|.|..|||..:...:::
  Rat   363 LLGHPKTKAFVTHGGANGIYESIHHGIPMVGIPLFAEQRDNVAHMVAKGAAVSLDFHTMSSSDLL 427

  Fly   420 LAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNV 484
            .|::.::...|||:....||...||||:..:|.|::|.|:::|||||.|:|.....::..||:::
  Rat   428 NALKAVINKPSYKKKVMWLSAIHHDQPLKPLDRAVFWIEFVMRHKGAKHLRPLAHNLAWYQYHSL 492

  Fly   485 DVVSVLFGRIGLSAIIVIFL 504
            ||:..|     |:.::.|.|
  Rat   493 DVIGFL-----LACVLAIVL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	120/480 (25%)
Ugt2b7	NP_775445.2	UDPGT	24..527	CDD:278624	132/519 (25%)