Protein Alignment Ugt303A1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_775417.1
• Gene: Ugt2b1 / 286954
• RGDID: 708541
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 138/520 - (26%)
• Similarity: 248/520 - (47%)
• Gaps: 51/520 - (9%)

  Fly    15 LLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLT-LISAVTIM--PHIEG--- 73
            ||..|:|.....|...:.|:...: |.::.|...|..|.||||::| |:|:.:|:  |..|.
  Rat    10 LLIQLICYFRPGACGKVLVWPTEY-SHWINIKIILNELAQRGHEVTVLVSSASILIEPTKESSIN 73

  Fly    74 --VHHIRVPKLDMLMKILLDFEYDTDLTKWT---EAQFLSEYFYNCSKFVLEDPGVQELLRNASA 133
              ::.:.:.|.|      |::.:...:.:||   |...:..|:....|...|...|.|.|..|..
  Rat    74 FEIYSVPLSKSD------LEYSFAKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVENLCKALI 132

  Fly   134 --KYSLIILEASHNDALYG---------FSQHFNAPLLGVAAYGSSWNID-FLVGNSAPSVYEPM 186
              |..:..|:.|..|.:..         .::....||:....:...:..: |..|...|..|.|:
  Rat   133 WNKSLMKKLQGSQFDVILADAVGPCGELLAELLKTPLVYSLRFCPGYRCEKFSGGLPLPPSYVPV 197

  Fly   187 SALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFP---GATTSIHDLRRRFSLVL 248
            .....:..:..:|:..|::    :.|...|.:.|.:...:.|.:.   |..|::.::..:..:.|
  Rat   198 VLSELSDRMTFVERVKNML----QMLYFDFWFQPFKEKSWSQFYSDVLGRPTTLTEMMGKADIWL 258

  Fly   249 INQHFTMGRVRSNVPNIVEVAGMHLDEKP-YPLDAELKKILDEA-EHGVIYFSMGLQLLDHWLPP 311
            |...:.:......:||...|.|:|.  || .||..|:::.:..: ||||:.||:|..:.:  |..
  Rat   259 IRTFWDLEFPHPFLPNFDFVGGLHC--KPAKPLPREMEEFVQSSGEHGVVVFSLGSMVKN--LTE 319

  Fly   312 GMRASMSDAFAQLKQQVIWKTD--YPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLI 374
            .....::.|.||:.|:|:|:.|  .|:.:..:..::  .|.||..:|.||..|.|:.|.|...:.
  Rat   320 EKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRLY--KWIPQNDLLGHPKTKAFVAHGGTNGIY 382

  Fly   375 ESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLS 439
            |::::.:|::.||||.||..|...|...|.|.::||..|....::.|::.::.:.|||.||..||
  Rat   383 EAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLS 447

  Fly   440 QRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFL 504
            :..||||:..:|.|::|.||::|||||.|:|....::|..||:::||:..|.    |..:.|:|:
  Rat   448 RIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLL----LCVVGVVFI 508

  Fly   505  504
              Rat   509  508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	120/468 (26%)
Ugt2b1	NP_775417.1	UDPGT	24..527	CDD:278624	133/506 (26%)