Protein Alignment Ugt303A1 and Ugt2b

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_113721.5
• Gene: Ugt2b / 24862
• RGDID: 3936
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 140/538 - (26%)
• Similarity: 233/538 - (43%)
• Gaps: 98/538 - (18%)

  Fly    30 ILAVF----SYTFGSSY---LLITP-----------FLRNLVQRGHQLTLISAVTIMPHIEGVHH 76
            |.|:|    ||.|.|.:   :|:.|           .|..||||||::|::.        ...:.
  Rat     6 ISALFLLQISYCFKSGHCGKVLVWPMDFSHWMNIKIILDELVQRGHEVTVLK--------PSAYF 62

  Fly    77 IRVPKLDMLMKILLDFE-YDTDLTK-------------WT----------EAQFLSEYFYNCSKF 117
            ...||....:|    || :.|.::|             ||          .:..|....|..|.|
  Rat    63 FLDPKKSSDLK----FEIFSTSISKDELQNHFIKLLDVWTYELPRDTCLSYSPILQNLVYEFSYF 123

  Fly   118 VLEDPGVQELLRNA-SAKYSLIILEASHNDALYG---------FSQHFNAPLLGVAAYGSSWNID 172
            .|      .:.::| |.|..:..|:.|..|.|:.         .::..:.|.|...::.....::
  Rat   124 YL------SICKDAVSNKQLMTKLQESKFDVLFADPVASCGDLIAELLHIPFLYSLSFSPGHKLE 182

  Fly   173 FLVGN-SAPSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERF---IYLPRQIDLYKQHFPGA 233
            ..:|. ..|..|.|:...|....:..|::..|:|.:    |...|   |...::.|.:.....|.
  Rat   183 KSIGKFILPPSYVPVILSGLAGKMTFIDRVKNMICM----LYFDFWFEILRHKEWDTFYSEILGR 243

  Fly   234 TTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHL-DEKPYPLDAELKKILDEAEHGVIY 297
            .|::.:...:..:.||..::.:......:||:..:.|:|. ..||.|.|.| :.:....||||:.
  Rat   244 PTTVDETMSKVEIWLIRSYWDLKFPHPTLPNVDYIGGLHCKPAKPLPKDME-EFVQSSGEHGVVV 307

  Fly   298 FSMGLQLLDHWLPPGMRASMSD--------AFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRA 354
            ||:|          .|.::|::        |.||:.|:|:||.|.........|.....|.||..
  Rat   308 FSLG----------SMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQND 362

  Fly   355 ILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIV 419
            ||.||..|.|:||.|...|.|::::.:|::.||||.||..|...|...|.|..|:.:.:.:.:.:
  Rat   363 ILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDNIAHMVAKGAAVSLNIRTMSKLDFL 427

  Fly   420 LAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNV 484
            .|:|:::.|..||:|...||...|||||..:|.|::|.|:|:|||||.|:|.....:...||:::
  Rat   428 SALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEFIMRHKGAKHLRPLGHNLPWYQYHSL 492

  Fly   485 DVVSVLFGRIGLSAIIVI 502
            ||:..|.....:.|.:.:
  Rat   493 DVIGFLLTCFAVIAALTV 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	129/499 (26%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	133/520 (26%)