DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303A1 and ugt-36

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_504820.2	Gene:	ugt-36 / 184266	WormBaseID:	WBGene00017315	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	561	Identity:	124/561 - (22%)
Similarity:	232/561 - (41%)	Gaps:	96/561 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLR----NLVQRGHQLTLISAVTI-----MPH 70
            |||.|.....:::.|.| ||...||.|:   |.|..    .|...||.:|..:...:     :.:
Worm    10 LLFCLFFALCSDSYNFL-VFCPLFGHSH---TTFFAKIADTLTYAGHNVTFFTPTIVRKFSKIQY 70

  Fly    71 IEGVHHI-RVPKLDMLMKILLDFEYDTDLTK-WTEAQFLSEYFYNCSKF---------------- 117
            ::.:.|: ::...|.|:|:...|| :.|::| |.....|||.......|
Worm    71 VKSITHVLQLDPSDRLVKLGSMFE-EKDVSKFWYRDSSLSEMLPMIDTFNNMFVEQAAVISRNLH 134

  Fly   118 VLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAY--------GSSWNIDFL 174
            ||:|  ::|:      .:.::|.|            ||..|...|..|        .:|...|:
Worm   135 VLDD--LKEM------NFDVMIFE------------HFVEPAYLVLDYLEIQKFIPATSLAFDY- 178

  Fly   175 VGNSAPSVYE-------PMSALGYTSGLNLIEKWHNLIY-ITEERLVERFIYLPRQIDLYKQHFP 231
              |...|:.|       |:....|:..::|.::..|.|. :..:.|:.:        :.|:.:.|
Worm   179 --NMVKSIGEPLMLSTVPLPTSEYSDRMSLPQRLINAINPLIFDNLIPK--------NKYRSYRP 233

  Fly   232 G-ATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLD---EKPYPLDAELKKILDEAE 292
            . |..:...:....|.|..|.:..:...|:.:...|:|.|:.:|   .|...:..|...:|:...
Worm   234 PYAPINTKSIEPFCSAVFTNSNPYIDYPRATLEKNVQVGGISVDIDKLKSQKVSNEWDAVLNLRP 298

  Fly   293 HGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQ-QVIWK--TDYPEMVNQSRNVFARTWFPQRA 354
            ..|: .|.|..:|...:|...:.:::....:... ..|||  |:.....|.:.|:....|.||.|
Worm   299 KTVL-VSFGSIMLSKDMPINNKITIATVLGKFPDVTFIWKYETNDTSFANGTENIHFSNWVPQTA 362

  Fly   355 ILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVA---RKLDFKNLFRD 416
            :|..|.:..|.|||||.|:.|..:...|.:..|:|.||.:|.|.:.:...:   .|.|..|  .|
Worm   363 LLADPRLSAFFTHAGLGSVNEVSYLGKPTIMCPIFADQMRNAKMLARHNGSIEISKYDLSN--GD 425

  Fly   417 EIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQY 481
            :|..|:..::::.|||..|..|:.:..:||:...:..:...|:..:......:....::||.:||
Worm   426 KIEEALSKILFDESYKTAAEKLAHQLANQPVKPKELLVRHAEFAAQFGHLPSLDPHSRQMSFIQY 490

  Fly   482 YNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATRHLEYRLNV 522
            :.:|:.:::...:    |:.:|:.:||..|....|.:.|::
Worm   491 FLIDLTAIILSTV----ILFLFVLFKLGKLMYSKLPFNLSL 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	108/491 (22%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	110/520 (21%)
ugt-36	NP_504820.2	Glycosyltransferase_GTB_type	6..507	CDD:299143	118/539 (22%)
ugt-36	NP_504820.2	YjiC	25..455	CDD:224732	104/468 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810