DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303A1 and ugt-7

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	566	Identity:	125/566 - (22%)
Similarity:	216/566 - (38%)	Gaps:	136/566 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FSYTFGSSYLLITP--------FLRN----LVQRGHQLTLISAVTIMPHIEGVHHIRVPKLDMLM 86
            :||.|  .||:|:|        |:.|    |...||::.:... .|:..:.....|:.|.:.
Worm    12 YSYAF--KYLIISPIYSYSHVKFMSNIADTLADHGHEVVVFQQ-QIVEALRDKKVIKNPDIK--- 70

  Fly    87 KILLDFEYDT------------DLTK-WTE------------AQFLSEYFYNCSKFVLEDPGVQE 126
              ::::|.:|            .:|| ||.            |:.:|:...:....|.||..:..
Worm    71 --IINYEANTAGKEFYRNRPKSSVTKYWTTNQAANPSAADQFAEAMSKDLEHMCLQVFEDKSLHT 133

  Fly   127 LLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMS-ALG 190
            :|:  |..:.:::.|......|| ...:...|...||              .|.|..:|:. |||
Worm   134 MLK--SEHFDVLLAEPFDPCGLY-LGDYLKIPSTIVA--------------MASSRIDPVQWALG 181

  Fly   191 YTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDL------RRRFSLVLI 249
            ..||||                     ::|.....|.:. .|....|:::      .|.|..|..
Worm   182 QPSGLN---------------------FIPGPDSKYGEE-SGVWDRINNVWMFFMRTRMFRAVYW 224

  Fly   250 N----QHFTMGRVRSNVPNIV-EVAGMHLDEKPY---------------------------PLDA 282
            |    ..|..|....|:..|| |.|.:..:..||                           .|..
Worm   225 NLLDKLRFKTGLEIRNIDEIVAESAYLFYNSNPYLDFPFPSLTKCVPIGGFSMNTTNWKSENLPE 289

  Fly   283 ELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQV--IWK----TDYPEMVNQS 341
            .||.||.:..: .::.|.|..:....:|...:.::.:. .:|...|  |||    .|.....|..
Worm   290 NLKNILQKRPN-TVFISFGSVIRSADMPQEYKNAIIEV-TKLMSDVTFIWKYEDEKDEEMRGNIP 352

  Fly   342 RNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLG--- 403
            .||....|.||.|:|....|.|||||.||.|::|..:...|.:.||||:||..|.:.:.:.|
Worm   353 ENVHLMKWLPQPALLADSRVSLFITHGGLGSIMEVAYSGKPAIVIPLFFDQPMNGEMLRRHGGAE 417

  Fly   404 VARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADH 468
            |..|.:..|  ..::...|::::.|..|..||:.||.....||::.::..:...|:....|....
Worm   418 VYSKFELSN--AKKLKKVIQNMIQNPKYLANAKKLSNLLQKQPINPIERLVKHAEFAAEFKKLPE 480

  Fly   469 MRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATR 514
            :....:.::..|::.:|:|:.|.....|||:.|.::.:.:.|:.::
Worm   481 LDPYSRHLNFFQFFFLDIVATLLILFMLSALFVYWITYVICSVRSK 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	115/515 (22%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	121/552 (22%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	115/515 (22%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	117/542 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810