DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303A1 and ugt-2

DIOPT Version :9

Sequence 1:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_505672.2	Gene:	ugt-2 / 179450	WormBaseID:	WBGene00007073	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	544	Identity:	122/544 - (22%)
Similarity:	220/544 - (40%)	Gaps:	92/544 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLTVLLFGLLCPKLTNAENILA----VFSYTFGSSYLLITPFLRNLVQRG-HQLTLISAVTIMPH 70
            ||..|.|.|.|       |:||    |.:..||.|::.....:.:.:..| |.:||:... |..|
Worm     5 LLVFLFFALYC-------NVLAYNYLVVAPVFGYSHMKFMNKVADTLANGKHNVTLLQTY-IYEH 61

  Fly    71 IEGVHHIRVPKLDML-----------------MKILLDFE-YDTDLTKWTEAQFL--SEYFYNCS 115
            ...:..::...::::                 .|...|.| .:..:|......|:  :|:...|.
Worm    62 WGKIRIVKNKNIEIIDYHNSENVPSNEQSASAFKFFWDNEIVNNPITGAMAPMFILYNEFKPMCD 126

  Fly   116 KFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNI--DFLVG-- 176
            :.:.:....|.:|.|   |:...:.|:....:|| ...|....||.:  :.:..|:  ...:|
Worm   127 RILTDKELHQWILSN---KFDGYVAESFDFCSLY-LGDHLKLNLLPM--FSTIKNVPGSHAIGEP 185

  Fly   177 ---NSAPSVYEPMSALGYTSGLNLIEKWHNLIYITE-----ERLVERFIYLPRQIDLYKQHFP-- 231
               |.|||:|     ..:.|...:.::..::...|.     ..|.||         .|:|.:.
Worm   186 SLLNYAPSLY-----TNFGSDQTVWDRIQDITAFTSFHYAFSNLFER---------QYRQAYDLL 236

  Fly   232 -GATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPY--PLDAELKKILDEAEH 293
             |...:..::.:..:....|.:..:|.....:...||:.|..:| .|:  .|:.|..|:||..:.
Worm   237 NGDVRTWREILQTATYFFYNNNPYIGFAMPTLEKSVEIGGFTID-PPHDLSLNEEFDKLLDLRKS 300

  Fly   294 GV-IYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQV-IWKTDYPE---MVNQSRNVFARTWFPQR 353
            .| |.|...:|..|  :|...::.:...||:|.... |||.:..:   ....|.|||.:.|.||.
Worm   301 TVLISFGTVVQSAD--MPENFKSGLIKMFAKLPDTTFIWKYEVEDAEFSKTLSENVFLKKWIPQP 363

  Fly   354 AILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVA---RKLDFKNLFR 415
            |:|..|.:.|||||.||.|.:|..:...|.|.||:|.||..|.|.:.:.|.|   .|.:.:|.
Worm   364 ALLADPRLNLFITHGGLGSTLEVAYAGKPSLMIPIFGDQMLNAKMLSRHGGAISYDKYELENY-- 426

  Fly   416 DEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQ 480
            :::...:::.:.|..|.:.|..|::..|:||:......:...|:..:......:.......:.::
Worm   427 EKLTETVKEAISNKEYNKKALLLAEILHNQPIDPKQNLLKHAEFTAKFGRVHALEPYSVHYNFIK 491

  Fly   481 YYNVDVVSVLFGRIGLSAIIVIFL 504
            ||.:|..::         ||:.||
Worm   492 YYMLDAYAI---------IIIFFL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	109/488 (22%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	111/512 (22%)
ugt-2	NP_505672.2	egt	15..498	CDD:223071	113/515 (22%)
ugt-2	NP_505672.2	UDPGT	31..530	CDD:278624	110/511 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810