Protein Alignment Ugt303A1 and ugt-17

DIOPT Version :9

• Sequence 1: NP_001262470.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001122841.1
• Gene: ugt-17 / 179406
• WormBaseID: WBGene00007422
• Length: 540
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 131/543 - (24%)
• Similarity: 237/543 - (43%)
• Gaps: 83/543 - (15%)

  Fly    15 LLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRN----LVQRGHQLTLISAVTIM--PHIEG 73
            :||.::  ..:|:..:| ||:..||:|:   :.||..    |:..||.:|::..:.:.  .|:.|
 Worm    10 ILFSII--DYSNSYKVL-VFNPAFGASH---SNFLGKISDILIDAGHDVTMLIPIAMQGKKHLVG 68

  Fly    74 ----VHHIRV---PKL----------DMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFVLED 121
                .:.||:   |:.          |:|.|.:...|.|..|.......|.....|.| :.|.:.
 Worm    69 SKKVKNIIRIDQDPRSIELYKQTGAEDVLRKKIWKVESDIALFFKMAGNFSKTCGYQC-QHVFQQ 132

  Fly   122 PGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPL---LGVAAYGSSWNIDFL------VGN 177
            ..:.|.|:|  ..:.|.|.|:..   :.|:      ||   |||....::.::.|:      :|.
 Worm   133 TEILEKLKN--EHFELGITESLF---ICGY------PLFDHLGVKTIINADSVLFMDIVKCTLGE 186

  Fly   178 SAPSVYEPMSALGYTSGLNLIEKWHNLI------YITEERLVERFIYLPRQIDLYKQHFPGATTS 236
            .:.|.:.|......|..:.|:|:..|.|      |.::.|..|       ::.:.:.::.|:.|
 Worm   187 PSSSTFYPALISPMTDKMTLVERIKNAIQMLIPVYFSKMRFEE-------ELSMIEPYYNGSKT- 243

  Fly   237 IHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPY---PLDAELKKILDEAEHGVIYF 298
            ..:|....:..::|.:..:......:|..|.:.||.:..|..   .|:.|...:|:..:..|: .
 Worm   244 WEELLENVAFNMVNSNRYLDYASPTLPKTVFIGGMQVKTKKQGTPKLNKEWDDLLNIRKENVL-V 307

  Fly   299 SMGLQLLDHWLPPGMRASMSDAFAQLKQ-QVIWKTDYPEMVNQS-----RNVFARTWFPQRAILN 357
            |.|.......:|...:.|..|.||.:.: ..|||.   |..|.:     .||...||.||..:|.
 Worm   308 SFGSNAFSSEMPDEFKKSFLDVFASMPEITFIWKY---EQENSTIAMHLSNVKMTTWMPQSDLLA 369

  Fly   358 HPNVKLFITHAGLLSLIESVHYAVP----LLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEI 418
            ...:.||:||.||.|.||..:...|    :..|||..||.:|...:.:.|.|.:||..||...::
 Worm   370 DNRLSLFVTHGGLGSSIELAYQGTPAVVNIFKIPLMADQPRNAHMLTRHGGAIQLDKTNLDNPQM 434

  Fly   419 VL-AIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYY 482
            :. ||:.::.|.||..|||.|:|...|||.:..:..:...::.::....|.::...:::::.|:|
 Worm   435 IRDAIKTILDNDSYTENARKLAQILEDQPYTPAEVVLKHCDFAVKFGVLDTLQSEGRKLNVFQFY 499

  Fly   483 NVDV-VSVLFGRIGLSAIIVIFL 504
            :.|: |.|.|..|.:...||:::
 Worm   500 SYDILVVVCFLIITVVVFIVLYV 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	119/490 (24%)
		UDPGT	39..507	CDD:278624	124/519 (24%)
ugt-17	NP_001122841.1	egt	1..513	CDD:223071	128/532 (24%)
		UDPGT	22..538	CDD:278624	128/529 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	161	1.000	Domainoid score	I2438
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.860