Protein Alignment Ugt303A1 and ugt-52

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_499988.1
• Gene: ugt-52 / 176904
• WormBaseID: WBGene00018931
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 129/546 - (23%)
• Similarity: 230/546 - (42%)
• Gaps: 69/546 - (12%)

  Fly     1 MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLIT-PFLRNLVQRGHQLTLISA 64
            :|..|..:.:...|.||.|  |::....::| .:....|.|::..| ..:.:||:.||.:.||.|
 Worm     7 IFFTPMTSPIRCLVFLFTL--PRVIQTLHVL-FYILLLGKSHIDFTDSLIESLVENGHTVDLIIA 68

  Fly    65 VTIMPHIEGVHHIRVPKLDML-MKILLDFEYDTDLTK--------------WTEAQFLSEYFYNC 114
                   ....|::....:|: .|....|:.::...|              |.|..:..:...:.
 Worm    69 -------RMNSHVKSNGTNMVTRKYTYGFQEESPWNKAPHLLNPFKGRERTWNEHTYYMDIVTDL 126

  Fly   115 SKFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAP-LLGVAAYGSSWNIDFLVG-- 176
            .:..|.|.|:...:  :|.||.:.|.....|..: ...:::..| ::.|::...........|
 Worm   127 CEIGLSDAGLHAFI--SSQKYDIGIATEYENCGV-ALMKYYKIPSIVSVSSLPILDRQSLAAGMP 188

  Fly   177 NS---APSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPR-QIDLYKQHFPGATTSI 237
            ||   ..:::|......|.........|.::..|...       |..: |.::.|:|. |.....
 Worm   189 NSPAVTQAIFEAEDLTTYWGKFRNFLNWAHITLIINP-------YCEKHQSEVIKKHL-GENFDT 245

  Fly   238 HDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAE--HGVIYFSM 300
            .:|.....|..:|.:..:...|.:...|..:.|::|.:....||.|::|::.:..  :|::.|..
 Worm   246 SNLIESLDLAFVNSNELIETPRVSSHKIKYIGGINLKKSKDRLDEEVEKVITQKPIGNGIVVFCF 310

  Fly   301 GLQLLDHWLPPGMRASMSDAFAQLKQ-QVIWKTDYPEMVNQSRNVFART-------WFPQRAILN 357
            |.|:.....|..:|.:.:.||..... ..:||.   ||.:....:||.|       |.||..:||
 Worm   311 GTQVPSSLFPIEVRRAFAQAFRHFPDFTFVWKY---EMQDGDEQIFANTTNLRLLKWLPQTDLLN 372

  Fly   358 HPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAI 422
            ....|.||:|.||.|.:||.:..||:|.:|||.||..|......:|....||...|....||..:
 Worm   373 DARTKAFISHVGLNSYLESSYAGVPILAVPLFADQPHNAFSGMSIGTTYMLDKTRLTTPNIVKGL 437

  Fly   423 EDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILR----HKGADHMRIAEQEMSLMQYYN 483
            |.::|::||..||:.:|:..|::|.......:.|.|:..|    |:   ::.:..|.||:.:||.
 Worm   438 EAVLYDSSYTLNAKRISKMLHERPNPPKKIFVEWIEFASRNPLLHR---NLNLIGQNMSVFEYYC 499

  Fly   484 VDVVSVLFGRIGLSAIIVIF---LGW 506
            :|::|  |..:.||.:|.:|   .||
 Worm   500 LDIIS--FCILLLSIVISVFYLGTGW 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	108/475 (23%)
ugt-52	NP_499988.1	GT1_Gtf-like	32..460	CDD:340817	103/449 (23%)