Protein Alignment Ugt303A1 and UGT3A2

DIOPT Version :9

• Sequence 1: NP_001262470.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_011512290.1
• Gene: UGT3A2 / 167127
• HGNCID: 27266
• Length: 550
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 149/560 - (26%)
• Similarity: 244/560 - (43%)
• Gaps: 90/560 - (16%)

  Fly    14 VLLFGLLCP--KLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLIS--AVTIMPHIEG- 73
            :||.|.|.|  .|:.|..||.: |...||.|||:....:.|...||.:|:::  ....||.:..
Human     7 LLLVGFLLPGVLLSEAAKILTI-STVGGSHYLLMDRVSQILQDHGHNVTMLNHKRGPFMPGLSDS 70

  Fly    74 -VHHIRVPKLDMLMKI----LLDF---EYDTDLTKWTEAQ------------FLSE------YFY 112
             ....|.|::..|.|.    |.||   |....:..|...:            ||.|      .|.
Human    71 PASASRYPRILYLQKYCQFGLKDFKKEEKSYQVISWLAPEDHQREFKKSFDFFLEETLGGRGKFE 135

  Fly   113 N-----------CSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLG---VA 163
            |           ||.| |....:.:.|:|.:  :.::|:|.      :.:.....|..||   ||
Human   136 NLLNVLEYLALQCSHF-LNRKDIMDSLKNEN--FDMVIVET------FDYCPFLIAEKLGKPFVA 191

  Fly   164 AYGSSW-NIDFLVGNSAPSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDL-- 225
            ...:|: :::|  |...|..|.|:.....|..::...:..|.:..        |.:..||..:
Human   192 ILSTSFGSLEF--GLPIPLSYVPVFRSLLTDHMDFWGRVKNFLMF--------FSFCRRQQHMQS 246

  Fly   226 -----YKQHF-PGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAG-MHLDEKPYPLDAE 283
                 .|:|| .|:...:..|..:..|..||..|.....|..:||.|.|.| |....||.|.|.|
Human   247 TFDNTIKEHFTEGSRPVLSHLLLKAELWFINSDFAFDFARPLLPNTVYVGGLMEKPIKPVPQDLE 311

  Fly   284 LKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWK---TDYPEMVNQSRNVF 345
             ..|....:.|.:..::| .:::....|.:...|::|||.|.|.||||   :.:|:.|:.:.||.
Human   312 -NFIAKFGDSGFVLVTLG-SMVNTCQNPEIFKEMNNAFAHLPQGVIWKCQCSHWPKDVHLAANVK 374

  Fly   346 ARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRME--KLGVARKL 408
            ...|.||..:|.||:::||:||.|..|::|::.:.||::.||||.||.:|..|:|  |.||:  :
Human   375 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVS--I 437

  Fly   409 DFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAE 473
            ..|.|..:.:.|.::.::.:..||..|...|......|:|.....:.|.:::|:..||.|::...
Human   438 QLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHLKPYV 502

  Fly   474 QEMSLMQYYNVDVVSVLFG-RIGLSAIIVIFLGWKLVSLA 512
            .:....:.|.:||...|.| .:|     .::|..||:.:|
Human   503 FQQPWHEQYLLDVFVFLLGLTLG-----TLWLCGKLLGMA 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	130/496 (26%)
		UDPGT	39..507	CDD:278624	136/526 (26%)
UGT3A2	XP_011512290.1	UDPGT	23..518	CDD:278624	135/518 (26%)
		egt	<162..517	CDD:223071	102/376 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740