Protein Alignment Ugt303A1 and UGT3A1

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_047272663.1
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 526
• Species: Homo sapiens
• Alignment Length: 518
• Identity: 132/518 - (25%)
• Similarity: 228/518 - (44%)
• Gaps: 76/518 - (14%)

  Fly    39 GSSYLLITPFLRNLVQRGHQLTLI--SAVTIMPHIEGV--------------HHIRVPK-LDMLM 86
            ||.|||:....:.|.:.||.:|::  |...::|.|:..              |..|:.| .|..:
Human    36 GSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYI 100

  Fly    87 KILLDFEYDTD-LTKWTEAQFLSEYFYNCSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYG 150
            :..||...::: |.|      |.|.|.....::|....:.:.|:|.:  |.|:.:||      :.
Human   101 ETALDGRKESEALVK------LMEIFGTQCSYLLSRKDIMDSLKNEN--YDLVFVEA------FD 151

  Fly   151 FSQHFNA-----PLLGV--AAYGSSWNIDFLVGNSAPSVYEPMSALGYTSGLNLIEKWHNLIYIT 208
            |.....|     |.:.:  ..:||   :||  |..:|..|.|:.....|..::...:..|.:..
Human   152 FCSFLIAEKLVKPFVAILPTTFGS---LDF--GLPSPLSYVPVFPSLLTDHMDFWGRVKNFLMF- 210

  Fly   209 EERLVERFIYLPRQIDL-------YKQHFP-GATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNI 265
                   |.:...|.|:       .|:||| |:...:..|..:..|..:|..|.....|..:||.
Human   211 -------FSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNT 268

  Fly   266 VEVAG-MHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVI 329
            |.:.| |....||.|.|.: ..|.:..:.|.:..:.|..|..|.....:: .|.:|||.|.|.||
Human   269 VYIGGLMEKPIKPVPQDLD-NFIANFGDAGFVLVAFGSMLNTHQSQEVLK-KMHNAFAHLPQGVI 331

  Fly   330 W---KTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYD 391
            |   .:.:|..|:.:.||....|.||..:|.||:::||:||.|..|::|::.:.||::.:|:..|
Human   332 WTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGD 396

  Fly   392 QFQNTKRM--EKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAI 454
            |..|..|:  :..||:.:|:  .:..|.:.|.::.::.:..||......|...|.||:|.....:
Human   397 QHGNMVRVVAKNYGVSIRLN--QVTADTLTLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLV 459

  Fly   455 WWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFG-RIGLSAIIVIFLGWKLVSLATRHL 516
            .|.::||:..||.|::....:....:.|.:||...|.| .:|     .::|..||:.:..|.|
Human   460 GWIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFLLGLTLG-----TMWLCGKLLGVVARWL 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	118/464 (25%)
UGT3A1	XP_047272663.1	Glycosyltransferase_GTB-type	36..526	CDD:471961	132/518 (25%)