Protein Alignment Ugt303A1 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 140/552 - (25%)
• Similarity: 241/552 - (43%)
• Gaps: 97/552 - (17%)

  Fly    11 LLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIEGVH 75
            :..:|..|.:  :|..||.:||:  ...||.:|.:...:.:|.|||:|:     |.:.|| ..:|
 Frog    14 VFALLFLGRV--QLIEAEKLLAI--PLDGSHWLSMRILVESLGQRGNQV-----VVLAPH-SNIH 68

  Fly    76 -HIRVPKLDMLMKILLDFEYDTDLTK----------WTEAQFLSE--------------YFYNCS 115
             |   |..:.::: .....|..:|.|          :|:...|.:              .|..|.
 Frog    69 IH---PSENYILR-TYPVPYSKELLKEQMVKSANDVFTKRPLLDKITNMYQRITNVTGIVFSACQ 129

  Fly   116 KFVLEDPGVQELLRNA--------SAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNID 172
            ..:.....:|||..:|        .....:|:.|..|..::|         ||    ||....||
 Frog   130 HLLHSKEIMQELQESAFDAALIDPFFPCGMIVAEYLHLPSVY---------LL----YGLPCGID 181

  Fly   173 FLVGN-SAPSVYEPMSALGYTSGLNLIEK------WH------NLIYITEERLVERFIYLPRQI- 223
            .|... .:|..|.|....|.|..::..::      |.      ||:|....:|...|::....|
 Frog   182 RLATQCPSPLSYVPRHFTGNTDHMSFPQRLKNALLWPVDTFLCNLLYSPYAQLASEFLHREMTIL 246

  Fly   224 DLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKIL 288
            .||.|      ||:.         |:...|.....|..:||:|.|.|::...:.: |:.|.:|::
 Frog   247 QLYSQ------TSVW---------LMKTDFVFDYPRPLMPNMVFVGGINCVGEQH-LNQEFEKLV 295

  Fly   289 DEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQ 352
            :.: |||.:.||:|..:.:  :|......:::|...:.|:|.|:.......|...|.....|.||
 Frog   296 NSSGEHGFVVFSLGSMVSE--IPMNKAMDIAEALKSIPQKVFWRYTGKAPPNLGENTHLVKWLPQ 358

  Fly   353 RAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDE 417
            ..:|.||..:.||||||...:.|.:..|||::.:|||.||..|.||:|..|....|:..::..::
 Frog   359 NDLLAHPKARAFITHAGSHGIYEGICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPED 423

  Fly   418 IVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYY 482
            :..|:..::.|..||.|.:.:|....|:|:..:|.|:.|.|:::|||||.|:|.|..:::..|||
 Frog   424 LSNAVRAVINNPVYKENIQRMSSLHLDRPIHPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYY 488

  Fly   483 NVDVVSVLFGRIGLSAIIVIFLGWKLVSLATR 514
            ::||:..|...:    :..:|:..|..:...|
 Frog   489 SLDVIGFLLAVL----LTALFISLKCCTFVFR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	122/486 (25%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	135/534 (25%)