Protein Alignment Ugt303A1 and ugt2a3

DIOPT Version :10

• Sequence 1: NP_652621.1
• Gene: Ugt303A1 / 53503
• FlyBaseID: FBgn0040252
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001170814.2
• Gene: ugt2a3 / 100384900
• ZFINID: ZDB-GENE-080721-22
• Length: 532
• Species: Danio rerio
• Alignment Length: 549
• Identity: 151/549 - (27%)
• Similarity: 261/549 - (47%)
• Gaps: 87/549 - (15%)

  Fly     1 MFSGPGIAGLLLTVLLFG---------LLCP-KLTNAENILAVFSYTFGSSYLLITPFLRNLVQR 55
            |.||    .||:.:||.|         |:.| :.::..|:.|:               :..||.|
Zfish     1 MTSG----ALLVCLLLCGVDVGWSGRVLVMPGEYSHWHNMRAI---------------IEALVDR 46

  Fly    56 GHQLTLI--SAVTIMPHIE------GVHHIRVPKLDMLMKILLDFEYDTDLTKW-----TEAQFL 107
            .|.:|::  |:...:||.:      .|..:.:.| :....:..||.|     .|     |:.:.:
Zfish    47 NHSVTVLVGSSSPTVPHTQKARFDYHVFKVNIEK-EEADAVWSDFIY-----LWMNETATKYETV 105

  Fly   108 SEYFYNCSKFV-LEDPGVQELLRNASAKYSLIILEASHNDALYG---------FSQHFNAPLLGV 162
            |..|...|:|: |.|    |:.:....:..|.:|..||.|.|:.         .:|..|.||:..
Zfish   106 SNIFQVMSRFMTLTD----EVCKGMFKEDLLQMLRESHYDVLFSDPMMPCSDLMAQTLNIPLVLS 166

  Fly   163 AAYGSSWNIDFLVGN-SAPSVYEPMSAL--GYTSGLNLIEKWHN-LIYITEERLVERFIYLPRQI 223
            .....:::.:.:.|. .||..|.|.::|  ..|..::.:|:..| |:|.:.:...:  :|:....
Zfish   167 LRATFAYSFERMCGQMPAPPSYVPAASLRDHLTDRMSFMERVENMLLYFSHDVFFK--LYMMFTF 229

  Fly   224 DLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKP-YPLDAELKKI 287
            |.......|..|::.:...:..:.||..::.....|...||...|.|:|.  || .||..|:::.
Zfish   230 DRIYTEIRGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHC--KPAKPLSKEMEEF 292

  Fly   288 LDEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIW----KTDYPEMVNQSRNVFAR 347
            :..: :|||:.||:|..:.:  |......:::.|..|:.|:|:|    ||  ||.:..:..::
Zfish   293 VQSSGDHGVVVFSLGSMIKN--LTSERANTIAAALGQIPQKVVWRYSGKT--PETLAPNTKIY-- 351

  Fly   348 TWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKN 412
            .|.||..:|.||..|.||||.|...|.|::::.||::.:|||.||..|...|:..|.|..||...
Zfish   352 DWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINT 416

  Fly   413 LFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMS 477
            |...::|.|::.::.|.|||.:...||:..|||||..:|.|::|.|:::|:|||.|:|:...|:|
Zfish   417 LESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELS 481

  Fly   478 LMQYYNVDVVSVLFGRIGLSAIIVIFLGW 506
            ..||:.:||.:.|   :.::|:|. || |
Zfish   482 WYQYHCLDVAAFL---LSIAALIT-FL-W 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303A1	NP_652621.1	Glycosyltransferase_GTB-type	26..465	CDD:471961	124/471 (26%)
ugt2a3	NP_001170814.2	UDPGT	21..519	CDD:278624	143/525 (27%)