Protein Alignment Ugt302K1 and Ugt1a6a

DIOPT Version :10

• Sequence 1: NP_652620.1
• Gene: Ugt302K1 / 53502
• FlyBaseID: FBgn0040251
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 538
• Identity: 160/538 - (29%)
• Similarity: 254/538 - (47%)
• Gaps: 80/538 - (14%)

  Fly    23 LMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPG-------------YTDVSVPNV 74
            |:|:...| ||:.....:.:.|.:.||.|.|  :.|:...:.|             |:...:...
Mouse    29 LLVVPQDG-SHWLSMKEIVEHLSERGHDIMV--LVPEVNLLLGESKYYRRKIFSVTYSLEELQTR 90

  Fly    75 IEVMGGDIGALWASIQ---KTYTQNLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFDAII----- 131
            ....|.:.....||:.   :.|..|:| ...|.|...:.|.:||....||:.|: |||:.
Mouse    91 FRTFGNNHFLPGASLMGPLREYRNNMI-VVDMFFSNCQSLLKDSATLSFLRENK-FDALFTDPAM 153

  Fly   132 -CETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVG-SPAPASFVPHIMLPFNDHMSLYERLL 194
             |...       |||:.|.|.:.|..|...: :..|:| ||:|.|:||.....|:|||:..:||.
Mouse   154 PCGVI-------LAEYLNLPSVYLFRGFPCS-LEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLA 210

  Fly   195 NVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYK---------MRRNASLVLINQHVSL--- 247
            |......|..|  ||                  |.|.         ::|:.||..::|: ||
Mouse   211 NFIVNILENYL--YY------------------CLYSKYEIIASDLLKRDVSLPSLHQN-SLWLL 254

  Fly   248 ------SFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHGAIYFSMGSNLKTKDLPPSK 305
                  .:|||..||||.:||::...| ..|.::.|.::|.| |||.:.||:||  ...::|..|
Mouse   255 RYDFVFEYPRPVMPNMIFLGGINCKKK-GKLTQEFEAYVNASGEHGIVVFSLGS--MVSEIPEKK 316

  Fly   306 VQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIY 370
            ..||.:|||.:.|.|||::......|..:|..:..|.||.|:|.|||..||:||.|.....|.|.
Mouse   317 AMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGIC 381

  Fly   371 HAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYR 435
            :..|::.:|:|.||..|....|..|.|:.|:...:.|.:...|::.:.:..||.:.:..:|..::
Mouse   382 NGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHK 446

  Fly   436 DQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVL-LIIFVVMVLLLIVLPITIYK 499
            |:...|::.|::|||:|.||:||.:|:.||..|.|:|||::||: .::.:|:.::.||.....|.
Mouse   447 DRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYG 511

  Fly   500 LLKKLLLKGERTQSTKVK 517
            ..|....||...:|.|.|
Mouse   512 CRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_652620.1	GT1_Gtf-like	24..448	CDD:340817	131/465 (28%)
Ugt1a6a	NP_659545.2	UDPGT	27..522	CDD:278624	157/529 (30%)