DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and ATG26

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_013290.1	Gene:	ATG26 / 850886	SGDID:	S000004179	Length:	1198	Species:	Saccharomyces cerevisiae

Alignment Length:	468	Identity:	99/468 - (21%)
Similarity:	170/468 - (36%)	Gaps:	134/468 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SLGYSSGYNY-LMVLNSAGRSHFNVGHALAKGLVKAGHTITVV--SVFP--------QKKPIPGY 66
            |:..:..|.: |:.:.|.|.....:  ||.|||:|.||.:.::  |.|.        |.:.|.|
Yeast   733 SIKPNKSYKFGLLTIGSRGDVQPYI--ALGKGLIKEGHQVVIITHSEFRDFVESHGIQFEEIAG- 794

  Fly    67 TDVSVPNVIEVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFDAII 131
                  |.:|:|                ..::::..|..::.|.  ..|.|:.::.:.......:
Yeast   795 ------NPVELM----------------SLMVENESMNVKMLRE--ASSKFRGWIDALLQTSWEV 835

  Fly   132 CETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFV---------PH-IMLPFNDH 186
            |    |...:.:.....:.::|:       .||:.:..|...:|.         || .::|....
Yeast   836 C----NRRKFDILIESPSAMVGI-------HITEALQIPYFRAFTMPWTRTRAYPHAFIVPDQKR 889

  Fly   187 MSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPG------------NKRCFYKMRRNASLV 239
            ...|..|.:|.|                |.::.:...|            .|...:.:::|....
Yeast   890 GGNYNYLTHVLF----------------ENVFWKGISGQVNKWRVETLGLGKTNLFLLQQNNVPF 938

  Fly   240 LINQHVSLSFPRPHSPNMIEVGG-MHIDGK--WNPLPEKIERFINESEHGA---IYFSMGSNL-- 296
            |.|...::..|.......:.|.| ..:|.|  :.| |.:::.||:|:....   :|...||.:
Yeast   939 LYNVSPTIFPPSIDFSEWVRVTGYWFLDDKSTFKP-PAELQEFISEARSKGKKLVYIGFGSIVVS 1002

  Fly   297 KTKDLPPSKVQEILKA-------------LGGLKQRVLWKFELD------NLPNKPENVYISDW- 341
            ..|::..:.|:.:::|             ||   .:...|.|:|      |:.|.|.     ||
Yeast  1003 NAKEMTEALVEAVMEADVYCILNKGWSERLG---DKAAKKTEVDLPRNILNIGNVPH-----DWL 1059

  Fly   342 FPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLN 406
            |||.|...|        |||..:|..|:....|.:..|.|.||||.....|..|.||.|  |.||
Yeast  1060 FPQVDAAVH--------HGGSGTTGASLRAGLPTVIKPFFGDQFFYAGRVEDIGVGIAL--KKLN 1114

  Fly   407 AVEFRKAIERITS 419
            |.....|::..|:
Yeast  1115 AQTLADALKVATT 1127

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	99/468 (21%)
ATG26	NP_013290.1	GRAM	194..>239	CDD:214725
		PH-GRAM1_AGT26	219..335	CDD:275402
		PH-GRAM2_AGT26	581..673	CDD:275403
		YjiC	739..1168	CDD:224732	98/462 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000