Protein Alignment Ugt302K1 and UGT8

DIOPT Version :9

• Sequence 1: NP_001287281.1
• Gene: Ugt302K1 / 53502
• FlyBaseID: FBgn0040251
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 155/548 - (28%)
• Similarity: 278/548 - (50%)
• Gaps: 46/548 - (8%)

  Fly     1 MRTFTLILGLLCS-LGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAG-HTITVVSVFPQKKPI 63
            |:::|....||.| :|.:.....::|......||..:...||..|.:.| ||:.::|......|.
Human     1 MKSYTPYFILLWSAVGIAKAAKIIIVPPIMFESHMYIFKTLASALHERGHHTVFLLSEGRDIAPS 65

  Fly    64 PGYTDVSVPNVIEVMGGDIGALWASIQKTYTQNL--------IDHYQMGFRITRGLFEDSNFQDF 120
            ..|:....|.:......| ..|.:.::..::..|        :|||.....:..|  ..:..|..
Human    66 NHYSLQRYPGIFNSTTSD-AFLQSKMRNIFSGRLTAIELFDILDHYTKNCDLMVG--NHALIQGL 127

  Fly   121 LKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGL---ATGGGLTFITDMVGSPAPASFVPHIMLP 182
            .|  :.||.::.:.  ||    :.....|.|:|:   ....||.:..: ||:|||.::||.....
Human   128 KK--EKFDLLLVDP--ND----MCGFVIAHLLGVKYAVFSTGLWYPAE-VGAPAPLAYVPEFNSL 183

  Fly   183 FNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLINQHVSL 247
            ..|.|:|.:|:.|.......|:.:.:..||..|::.:::....::..|.:...:||.::...|:|
Human   184 LTDRMNLLQRMKNTGVYLISRLGVSFLVLPKYERIMQKYNLLPEKSMYDLVHGSSLWMLCTDVAL 248

  Fly   248 SFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFIN-ESEHGAIYFSMGSNLK--TKDLPPSKVQEI 309
            .||||..||::.|||: :....:||||.::|::| .:|||.:..|.|:.:|  ::|:    ..::
Human   249 EFPRPTLPNVVYVGGI-LTKPASPLPEDLQRWVNGANEHGFVLVSFGAGVKYLSEDI----ANKL 308

  Fly   310 LKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKP 374
            ..|||.|.|:|:|:|......|...|..:.:|.||.|:|.|.||.||::|||:.|..|:|||..|
Human   309 AGALGRLPQKVIWRFSGPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIYHGVP 373

  Fly   375 VIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQ 439
            |:|:|:|.|.:..|...:..|.||:|::||:...|..:|:.::.:.|||.:..|.:|..::||..
Human   374 VVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPG 438

  Fly   440 TPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLP-IT--IYKLL 501
            .|:...|||::::.||.||.:|::|..::::.||..:|:..::.:...||..:|. :|  ||:.:
Human   439 HPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLDIAFVLLLGAALLYFLLSWVTKFIYRKI 503

  Fly   502 KKLLLKGERTQ----------STKVKRN 519
            |.|..:.:.:.          :.|.|||
Human   504 KSLWSRNKHSTVNGHYHNGILNGKYKRN 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	143/494 (29%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	143/497 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150679
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.740