Protein Alignment Ugt302K1 and UGT2B17

DIOPT Version :9

• Sequence 1: NP_001287281.1
• Gene: Ugt302K1 / 53502
• FlyBaseID: FBgn0040251
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001068.1
• Gene: UGT2B17 / 7367
• HGNCID: 12547
• Length: 530
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 152/560 - (27%)
• Similarity: 261/560 - (46%)
• Gaps: 98/560 - (17%)

  Fly     6 LILGLLCSLGYSSGYNYLMVLNSAGR--------SHFNVGHALAKGLVKAGHTITVVSVFPQKKP 62
            |::.|.|.  :|||        |.|:        ||:.....:.:.||:.||.:.|::
Human    10 LLMQLSCY--FSSG--------SCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLT------- 57

  Fly    63 IPGYTDVSVPNVIEVMGGDIGALWASIQKT-YTQNLIDHYQM------GFRITRGLF-------- 112
                   |..::: |......|:...:..| .|:|.::.:.|      .:.|::..|
Human    58 -------SSASIL-VNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQ 114

  Fly   113 --------------EDS--NFQDFLKSNQS-FDAIICETFYNDAHYGLAEHFNAPL-------IG 153
                          ||:  |.:...|..:| ||.::.:. .|.....|||..|.|.       :|
Human   115 ELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLADA-VNPCGELLAELLNIPFLYSLRFSVG 178

  Fly   154 LA---TGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQE 215
            ..   .|||..|         |.|:||.:|...:|.|...||:.|:.::.|    .|::|.....
Human   179 YTVEKNGGGFLF---------PPSYVPVVMSELSDQMIFMERIKNMIYMLY----FDFWFQAYDL 230

  Fly   216 KLYKEFFP---GNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIE 277
            |.:.:|:.   |.....::....|.:.||..:....||||..||:..|||:|.... .|||:::|
Human   231 KKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPA-KPLPKEME 294

  Fly   278 RFINES-EHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNK-PENVYISD 340
            .|:..| |:|.:.||:||.:  .::.......|..||..:.|:|||:|: ...||. ..|..:..
Human   295 EFVQSSGENGIVVFSLGSMI--SNMSEESANMIASALAQIPQKVLWRFD-GKKPNTLGSNTRLYK 356

  Fly   341 WFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTL 405
            |.||.|:|.|||..||:||||.....|:|||..|::|:|:|:||..|:||.:..|..:.:|.:|:
Human   357 WLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTM 421

  Fly   406 NAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNW 470
            ::.:...|::.:.::|.|.:.:..:|..:.||...|::.|::|:|.|.||:||.:|:.||..|.|
Human   422 SSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTW 486

  Fly   471 WQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGER 510
            .|||::||:..:...:..::.::........:||...|::
Human   487 IQYHSLDVIAFLLACVATMIFMITKCCLFCFRKLAKTGKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	149/528 (28%)
UGT2B17	NP_001068.1	UDPGT	24..518	CDD:278624	142/526 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150265
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690