Protein Alignment Ugt302K1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_652620.1
• Gene: Ugt302K1 / 53502
• FlyBaseID: FBgn0040251
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 560
• Identity: 154/560 - (27%)
• Similarity: 267/560 - (47%)
• Gaps: 92/560 - (16%)

  Fly     7 ILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVSV 71
            :|.||.:|.::.| ..::|....| ||:.....:.:.|...||...|::
  Rat    13 LLLLLYALPWAEG-GKVLVFPMEG-SHWLSMRDVVRELHARGHQAVVLA---------------- 59

  Fly    72 PNV-IEVMGGDIGALWASIQKTYTQNLIDHYQMGFR--ITRGL---FEDSNF-QDFLKSNQ---S 126
            |.| :.:...|...|     :||.   :.:.:.|||  :.|.:   ||..|: :.||::::   :
  Rat    60 PEVTVHIKEEDFFTL-----QTYP---VPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKN 116

  Fly   127 FDAIICETFYNDAHYG-LAEHFN-------------------APLIGLATGGGLTFI-----TDM 166
            ...::..:..|..|.| |.:|.|                   |..:|:.|...|.:|     ::.
  Rat   117 ISTVLLRSCMNLLHNGSLLQHLNSSSFDMVLTDPVIPCGAVLAKYLGIPTVFFLRYIPCGIDSEA 181

  Fly   167 VGSPAPASFVPHIMLPFNDHMSLYERLLNVAF---LGYERVLLDYYFLPTQEKLYKEFFPGNKRC 228
            ...|.|:|::|:::...:|||:..:|:.|:.:   |.|    :.::.....|.|..|.
  Rat   182 TQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLALKY----ICHFSFTRYESLASEL------- 235

  Fly   229 FYKMRRNASLVLINQHVSL---------SFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES- 283
               ::|..|||.:..|.|:         .:|||..|||:.:||::...| .||.::.|.::|.|
  Rat   236 ---LQREVSLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIK-KPLSQEFEAYVNASG 296

  Fly   284 EHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDIL 348
            |||.:.||:||  ...::|..|..||.:|||.:.|.|||::......|..:|..:..|.||.|:|
  Rat   297 EHGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLL 359

  Fly   349 AHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKA 413
            .|||..||:||.|.....|.|.:..|::.:|:|.||..|....|..|.|:.|:...:.|.:...|
  Rat   360 GHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENA 424

  Fly   414 IERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDV 478
            ::.:.:..||.:.:..:|..::|:...|::.|::|||:|.||:||.:|:.||..|.|:|||::||
  Rat   425 LKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDV 489

  Fly   479 L-LIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTKVK 517
            : .::.:|:.::.||.....|...|....||...:|.|.|
  Rat   490 IGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_652620.1	GT1_Gtf-like	24..448	CDD:340817	121/471 (26%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	146/537 (27%)