DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302K1 and ugt5g1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001107914.1	Gene:	ugt5g1 / 570913	ZFINID:	ZDB-GENE-080305-10	Length:	528	Species:	Danio rerio

Alignment Length:	521	Identity:	147/521 - (28%)
Similarity:	247/521 - (47%)	Gaps:	57/521 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRTFTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVS-----VFPQK 60
            :...|.:|.::|.   ..|.| ::|....| ||:.....:.:.|...||:.|||.     ...:.
Zfish     8 LSALTCLLSVVCC---CHGGN-ILVFPEDG-SHWVNMQVILRKLHTHGHSFTVVRSSKSWYIHEN 67

  Fly    61 KPIPGYTDVSVPNVIEVMGGDIGALWASI--------------------QKTYTQNLIDHYQMGF 105
            ..:  |..::| |.:|.  .|:|..:.::                    ||..|..|...:....
Zfish    68 SAL--YNTITV-NPVET--EDVGQDYFNMLLDRSLALQKMSPLVRFFEQQKDITTVLKVFHNGVL 127

  Fly   106 RITRGLFEDSNFQDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLI----GLATGGGLTFITDM 166
            |:...:.:|:.....|: ...||.::.:..: .|...:|.....|::    .|..|.     ..|
Zfish   128 RMVSAMLDDAELVKSLR-EAKFDLLLTDPAF-PAGVLVANFLQLPMVYNVRWLNAGD-----AHM 185

  Fly   167 VGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLD--YYFLPT-QEKLYKEFFPGNKRC 228
            ..:|:|.|:||......:|.||..:|:.|  ||.|...||.  |..:|. :|.|.:.|.||:.
Zfish   186 QTAPSPPSYVPMYNSLLHDQMSFLQRVEN--FLRYLCSLLQERYVIVPIYRELLERHFPPGSD-- 246

  Fly   229 FYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHGAIYFSM 292
            ...|:::|.:.|:.......||||..||:|.:||...... ..||..:|.|:..| |||.::.|:
Zfish   247 LLSMQQSADIWLMRMDFVFDFPRPTMPNIIYMGGFQCKPA-QALPVDLEEFMQSSGEHGVVFMSL 310

  Fly   293 GSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFV 357
            |:.:..  ||.:..:.|..|...:.|:|:|::..:.......|..:.:||||.|:|.|||..|||
Zfish   311 GAMVGA--LPRTITEAIASAFAKIPQKVMWRYHGERPSTLGNNTLLLEWFPQNDLLGHPKTRAFV 373

  Fly   358 THGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPS 422
            :|||.....|:|||..||:.||:..|||.|:...:......:|...||.:.||.:.::.:...|.
Zfish   374 SHGGTNGIYEAIYHGVPVLALPLLFDQFDNVMRLQVRNAARVLQVATLTSQEFLEGLKDVLENPL 438

  Fly   423 YTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMV 487
            |...::.:|..:|||..:|:::|.:|:|:|.||:|||:|:|.|..|.|:.||::|||:.:..:.|
Zfish   439 YRSSIRKMSELHRDQPISPLDSATFWIEYVMRHKGAAHLRSEANNLAWYSYHSLDVLVFLLAIAV 503

  Fly   488 L 488
            :
Zfish   504 I 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	145/511 (28%)
ugt5g1	NP_001107914.1	UDPGT	24..526	CDD:278624	143/502 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584643
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.790