DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302K1 and ugt5g2

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001186305.1	Gene:	ugt5g2 / 556049	ZFINID:	ZDB-GENE-081028-66	Length:	534	Species:	Danio rerio

Alignment Length:	514	Identity:	149/514 - (28%)
Similarity:	239/514 - (46%)	Gaps:	61/514 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLCSLGYSSGYN--YLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQ---KKPIPGYTDV 69
            ||.||  .||||  .::|....| ||:.....|.|.|...||.::|:.:...   |...|.|:.:
Zfish    14 LLLSL--PSGYNADKILVFPIDG-SHWVNMEVLVKKLQSRGHELSVIRLEDSWFIKGNSPYYSSI 75

  Fly    70 SVPNVIEVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFD-AIICE 133
            :|....:.:..|       :.:|..:.::|..:.| .|...|.:.|.|...||.....: |::..
Zfish    76 TVTLKKKFIDLD-------LFETAVKKILDARRDG-PIMGVLAQMSEFIGILKVGHGANIAMLTS 132

  Fly   134 TFYND--------AHYG-------------LAEHFNAPLI----GLATGGGLTFITDMVGSPAPA 173
            ...|.        |:|.             ||.:.:.|::    .::.|.|...|     :|:|.
Zfish   133 MLENKVLMSQIKMANYDLMLTDPAMPGGVILAHYLHLPMVYNVRWMSFGEGHFSI-----APSPI 192

  Fly   174 SFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASL 238
            ||||.......|.|.|.||..|....|...:...:..:|....|....||.... ...|:|:|.|
Zfish   193 SFVPVPGSGLTDRMGLLERSRNFLHYGLNLIQERWMVIPMYTSLLLNHFPPGTD-LLTMQRSAEL 256

  Fly   239 VLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHGAIYFSMGSNLKTKDLP 302
            .|:.......||||..||::.:||...... .|||..:|.|:..| :||.:..|:|:.:  ..||
Zfish   257 WLVRADFVFEFPRPSMPNLVYIGGFQCRPA-KPLPADLEEFMQSSGDHGVVVMSLGTLI--AGLP 318

  Fly   303 PSKVQEILKALGGLKQRVLWKFELDNLPNKP----ENVYISDWFPQTDILAHPKIMAFVTHGGML 363
            ...::.|..|...:.|:|:|:|    :..:|    .|..:..|.||.|:|.|||..|||.|||..
Zfish   319 KEVMEAIASAFAQIPQKVIWRF----IGQRPSTLGNNTLLIQWLPQNDLLGHPKTRAFVAHGGTN 379

  Fly   364 STTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQ 428
            ...|:|||..||:|||:..||..|:...:..|...|||..|.:..||..|:..|...|:|.:.:|
Zfish   380 GLYEAIYHGVPVLGLPLLFDQLDNIVRLQARGGARMLDAATCSTKEFLVALTDILENPTYRQNMQ 444

  Fly   429 GISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVL-LIIFVVM 486
            .:|..:||:...|::.|:||:|.|.|::||.:|::.|..::.:.|:.:||: |::|:::
Zfish   445 KLSNLHRDRPLHPLDKAVYWIEFVLRNKGAPHLRAEAYNVSEFSYYCLDVVALVLFMLL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	147/506 (29%)
ugt5g2	NP_001186305.1	egt	3..507	CDD:223071	149/514 (29%)
ugt5g2	NP_001186305.1	UDPGT	25..513	CDD:278624	141/501 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584644
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.690