Protein Alignment Ugt302K1 and UGT1A3

DIOPT Version :9

• Sequence 1: NP_001287281.1
• Gene: Ugt302K1 / 53502
• FlyBaseID: FBgn0040251
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_061966.1
• Gene: UGT1A3 / 54659
• HGNCID: 12535
• Length: 534
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 136/479 - (28%)
• Similarity: 223/479 - (46%)
• Gaps: 82/479 - (17%)

  Fly    92 TYTQNLIDHYQMGFRITRGLFEDSNF-QDFLKS-----NQS--FDAIICETFYNDAHYGLAEHFN 148
            ::||:..|.:.:|.  |:..||..:| :.|.:|     |.|  :.....|..:|:|   |..|.|
Human    83 SWTQDEFDRHVLGH--TQLYFETEHFLKKFFRSMAMLNNMSLVYHRSCVELLHNEA---LIRHLN 142

  Fly   149 APLIGLATGGGLTFITDMVG-------------------------------SPAPASFVPHIMLP 182
            |....:.       :||.|.                               .|.|:|::|.::..
Human   143 ATSFDVV-------LTDPVNLCAAVLAKYLSIPTVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTT 200

  Fly   183 FNDHMSLYERLLNVAF---LGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLINQH 244
            .:|||:..:|:.|:.:   |.|    :.:.|......|..|.|          :|..|:|.|..|
Human   201 NSDHMTFMQRVKNMLYPLALSY----ICHAFSAPYASLASELF----------QREVSVVDILSH 251

  Fly   245 VS---------LSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHGAIYFSMGSNLKTK 299
            .|         :.:|||..|||:.:||::...: .||.::.|.:||.| |||.:.||:||  ...
Human   252 ASVWLFRGDFVMDYPRPIMPNMVFIGGINCANR-KPLSQEFEAYINASGEHGIVVFSLGS--MVS 313

  Fly   300 DLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLS 364
            ::|..|...|..|||.:.|.|||::......|...|..:..|.||.|:|.||...||:||.|...
Human   314 EIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHG 378

  Fly   365 TTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQG 429
            ..|||.:..|::.:|:|.||..|....|..|.|:.|:...:.:.:...|::.:.::.||.:.:..
Human   379 VYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 443

  Fly   430 ISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVL-LIIFVVMVLLLIVL 493
            :|..::|:...|::.|::|||.|.||:||.:|:.||..|.|:|||::||: .::.||:.:..|..
Human   444 LSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITF 508

  Fly   494 PITIYKLLKKLLLKGERTQSTKVK 517
            ....|...|.|..||...::.|.|
Human   509 KCCAYGYRKCLGKKGRVKKAHKSK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	126/440 (29%)
UGT1A3	NP_061966.1	UDPGT	29..525	CDD:278624	134/470 (29%)
		egt	<262..508	CDD:223071	86/248 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150609
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.790