Protein Alignment Ugt302K1 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_001287281.1
• Gene: Ugt302K1 / 53502
• FlyBaseID: FBgn0040251
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 554
• Identity: 162/554 - (29%)
• Similarity: 268/554 - (48%)
• Gaps: 80/554 - (14%)

  Fly     4 FTLILGLLCSLG--YSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVS----------- 55
            :|.:| ||..||  :|||....:::.:...||:.....:.|.||:.||.:||::
Human     5 WTSVL-LLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPND 68

  Fly    56 -------VFPQKKPIPGYTDVSVPNVI--EVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGL 111
                   |:|     ...|.....|:|  :|      ..|:.|||       |.:.:.|...:.:
Human    69 AFTLKLEVYP-----TSLTKTEFENIIMQQV------KRWSDIQK-------DSFWLYFSQEQEI 115

  Fly   112 ---FEDSNFQDFLK---SNQS---------FDAIICETFYNDAHYGLAEHFNAPLI-GLATGGGL 160
               |.|. |::|.|   ||:.         ||.|..:.|:..... ||...|.|.: .|....|.
Human   116 LWEFHDI-FRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGEL-LAALLNIPFVYSLCFTPGY 178

  Fly   161 TFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFP-- 223
            |......|...|.|::|.:|...:|.|:..||:.|:.::.|    .|::|.....|.:.:|:.
Human   179 TIERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLY----FDFWFQMCDMKKWDQFYSEV 239

  Fly   224 -GNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINES-EHG 286
             |.....::....|.:.|:....|..||.|..||:..|||:|.... .|||:::|.|:..| |:|
Human   240 LGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPA-KPLPKEMEEFVQSSGENG 303

  Fly   287 AIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPE----NVYISDWFPQTDI 347
            .:.||:||.:  .::...:...|..||..:.|:|||:|:    .|||:    |..:..|.||.|:
Human   304 VVVFSLGSVI--SNMTAERANVIATALAKIPQKVLWRFD----GNKPDALGLNTRLYKWIPQNDL 362

  Fly   348 LAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRK 412
            |..||..||:||||.....|:|||..|::|:|:|.||..|:||.:..|..:.|||.|:::.:...
Human   363 LGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLN 427

  Fly   413 AIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVD 477
            |::.:.::|||.:.|..:|....||...|:..|::|:|.|..|:||.:|:.||:.|.|:|||::|
Human   428 ALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLD 492

  Fly   478 VL-LIIFVVMVLLLIVLPITIYKLLKKLLLKGER 510
            |: .::..|..::.:|....:: ...|...||::
Human   493 VIGFLLACVATVIFVVTKFCLF-CFWKFARKGKK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	157/522 (30%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	153/532 (29%)
		egt	<269..506	CDD:223071	89/243 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150513
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690