DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt37C1

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	163/485 - (33%)
Similarity:	253/485 - (52%)	Gaps:	27/485 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 AKGLVKAGHTITVVSVFPQK----------KPIPGYTDVSVPNVIEVMGGDIGALWASIQKTYTQ 95
            ||.|.:|||.:||||:...|          .|:....:.::.|.:..|.|....:   |...|.
  Fly     4 AKALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNI---ITTMYL- 64

  Fly    96 NLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGL 160
             |::...:.......|.:|..||...::  .||.:|..:|:||...|:|.....|:|........
  Fly    65 -LLNGLDVMVTSQADLLKDPRFQRVFET--KFDLMILGSFFNDFQLGVAGKLKVPVIVDWMIPSN 126

  Fly   161 TFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNV---AFLGYERVLLDYYFLPTQEKLYKEFF 222
            |.|.:.|.:|:..|:||:........||.::|..|:   ..|.|..:..:|.|    .::|.|.|
  Fly   127 TMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKF----NRIYNEIF 187

  Fly   223 PG-NKRCFYKMRRNASLVLINQHVSLSFP-RPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEH 285
            .. :.....:|::|.|:|.:..|:....| ||..|.:|||||:.:..:.:|||:.||:|:..|..
  Fly   188 TDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQ 252

  Fly   286 GAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFE-LDNLPNKPENVYISDWFPQTDILA 349
            |||:.|.|||:|:..:.|..|..:.|.|.||||.|:||:| |:|.|....|::..||.||.||||
  Fly   253 GAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYKDWLPQDDILA 317

  Fly   350 HPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAI 414
            ||....||||.|..|.|||.||..|::.||||.|...|.|....:|||:.||.:|:....||:||
  Fly   318 HPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAI 382

  Fly   415 ERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVL 479
            ..:.....||:.|:..|..|||:..||.::.::||::|.||.||..|:|.|..:.:.:.||:|:.
  Fly   383 NEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIY 447

  Fly   480 LIIFVVMVLLLIVLPITIYKLLKKLLLKGE 509
            .::..:::.|:.:..:|:..|..|||.|.:
  Fly   448 ALVLAILIFLVFLTRLTVKFLFSKLLGKAK 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	156/454 (34%)
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	163/483 (34%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	150/437 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445743
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850