DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302K1 and Ugt37C2

DIOPT Version :9

Sequence 1:	NP_001287281.1	Gene:	Ugt302K1 / 53502	FlyBaseID:	FBgn0040251	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	166/531 - (31%)
Similarity:	272/531 - (51%)	Gaps:	36/531 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTD 68
            |.|:||::.|   :.|.|.|.:.:|...||..:..::||.||||||.:||||:.   ||...:.|
  Fly     8 FLLLLGVVAS---TQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSML---KPKVTHKD 66

  Fly    69 VS---VP------NVIE----VMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNFQDF 120
            :.   ||      .::|    .|.|...:|.:::.:     |:....:.......|..|..||..
  Fly    67 IHLIVVPMKEEQERIMEDQMTEMAGQKNSLVSTMYR-----LLTSMDVMINAQAELLSDPRFQRI 126

  Fly   121 LKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFND 185
            .::  .||.:|...|.||...|:|.....|:|.......:..|....|:|:..|:||.:......
  Fly   127 YET--KFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQ 189

  Fly   186 HMSLYERLLNVAFLGYERVLLDYYFLPTQEKL---YKEFFPGNKRCFYK-MRRNASLVLINQHVS 246
            .|...:|..|    ..:.:|.::.|:....||   |.:.||.......| :|:|.|:..:..|:.
  Fly   190 PMGFLKRTEN----ALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSHLI 250

  Fly   247 LSFP-RPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEIL 310
            ...| ||..|.:||:||:.:..|.:|||:.|::||:.::.||::.|:|||:|:..:.|..||.|.
  Fly   251 SEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQFISNAKQGAVFLSLGSNVKSSTVRPEIVQIIF 315

  Fly   311 KALGGLKQRVLWKFE-LDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKP 374
            |.|..||:.|:||:| |:|.|....|:...:|.||.||||||....|:||.|....||:.||..|
  Fly   316 KVLSELKENVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVP 380

  Fly   375 VIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQ 439
            ::.||||.||..|.|..|::|||:.||..::.....|.|::.:.....|.:.:...|..|||:..
  Fly   381 MVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPM 445

  Fly   440 TPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKL 504
            |..::.::|.|::.|||||..|:|.:..:|:.|.:|:|:..:|..::||.:::..:....:..|.
  Fly   446 TAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKF 510

  Fly   505 LLKGERTQSTK 515
            ..|.:.:|:.|
  Fly   511 GGKAKISQTKK 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302K1	NP_001287281.1	egt	1..480	CDD:223071	159/494 (32%)
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	153/475 (32%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	155/495 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445687
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850